182028
Poly(ethylene glycol)
average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor
Synonym(s):
Polyethylene oxide, PEO
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About This Item
Linear Formula:
(-CH2CH2O-)n
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
Product Name
Poly(ethylene oxide), average Mv 600,000 (nominal), powder
Quality Level
form
powder
mol wt
average Mv 600,000 (nominal)
contains
200-500 ppm BHT as inhibitor
greener alternative product characteristics
Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
viscosity
4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)
transition temp
Tm 65 °C
Ω-end
hydroxyl
α-end
hydroxyl
application(s)
battery manufacturing
greener alternative category
SMILES string
[H]OCCO
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
General description
Poly(ethylene oxide)(PEO) is a high molecular weight, non-ionic water-soluble polymer. It forms agel on hydration and shows good swelling capacity. PEO polymers are non-toxicand widely used in drug delivery systems to enhance drug solubility.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.
Application
Poly(ethylene oxide) can be used to prepare:
- Bioabsorbable and injectable hydrogels for sustained drug release.
- PEO/graphene oxide composite electrolyte membrane for fuel cells.
- Poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. Losartan potassium encapsulated (PEO-b-PCL) copolymer can be used as a drug carrier.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro