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Merck

251682

Sodium 3-mercapto-1-propanesulfonate

technical grade, 90%

Synonym(s):

3-Mercapto-1-propanesulfonic acid sodium salt, MPS

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About This Item

Linear Formula:
HSCH2CH2CH2SO3Na
CAS Number:
17636-10-1
Molecular Weight:
178.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24855149
EC Number:
241-620-3
Beilstein/REAXYS Number:
5362242
MDL number:
MFCD00043148
Assay:
90%
Form:
powder

Key Documents

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InChI key

FRTIVUOKBXDGPD-UHFFFAOYSA-M

InChI

1S/C3H8O3S2.Na/c4-8(5,6)3-1-2-7;/h7H,1-3H2,(H,4,5,6);/q;+1/p-1

SMILES string

[Na+].[O-]S(=O)(=O)CCCS

grade

technical grade

assay

90%

form

powder

mp

~220 °C (dec.) (lit.)

solubility

water: soluble 50 mg/mL, colorless

functional group

sulfonic acid

Quality Level

200

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Application

Sodium 3-mercapto-1-propanesulfonate (MPS) can be used to prepare tetrasubstituted organosilicon thioether by photochemical reaction with tetravinylsilane via thiol-ene reaction. It can also be used as a capping agent to functionalize gold nanoparticles for potential applications in the field of radiotherapy and drug delivery.
MPS can be also used in the preparation of Rh nanoparticles by liquid-phase reduction of rhodium (III) chloride.

General description

Sodium 3-mercapto-1-propanesulfonate forms self assembled monolayer via chemisorption on a gold-coated substrate.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

159.8 °F - closed cup

flash_point_c

71 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBK6381
STBK5367
STBJ4663
STBG7616
STBF4815V

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Naoyuki Sakamoto et al.
Nanoscale, 1(1), 106-109 (2010-07-21)
Highly dispersed rhodium nanoparticles (1.7 +/- 0.3 nm) prepared by a liquid-phase reduction method were loaded on a solid solution of GaN and ZnO without forming aggregates, achieving improved activity for visible-light-driven overall water splitting when the nanoparticles are coated
Mieke Aldenhoven et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(6), 1106-1109 (2015-02-25)
Allogeneic hematopoietic cell transplantation (HCT) is the only treatment able to prevent progressive neurodegenerative disease in a selected group of mucopolysaccharidosis (MPS) disorders. However, its use was historically limited by the high risk of graft failure and transplantation-related morbidity and
Nucleobases functionalized quantum dots and gold nanoparticles bioconjugates as a fluorescence resonance energy transfer (FRET) system-Synthesis, characterization and potential applications
Rodzik-Czalka L, et al.
Journal of Colloid and Interface Science, 514(20), 479-490 (2018)
J Tie et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 26(8), 1715-1722 (2015-04-09)
Early indicators of treatment response in metastatic colorectal cancer (mCRC) could conceivably be used to optimize treatment. We explored early changes in circulating tumor DNA (ctDNA) levels as a marker of therapeutic efficacy. This prospective study involved 53 mCRC patients
Geoffrey J Ashwell et al.
Faraday discussions, 131, 23-31 (2006-03-04)
The chevron-shaped dye, N-butyl-2,6-bis-[2-{4-(2-(4-dibutylaminophenyl)-vinyl)-phenyl}-vinyl]-pyridinium iodide, has a hydrophilic apex that is electron-accepting and hydrophobic it-bridged limbs that are electron-donating. It forms non-centrosymmetric monolayers at the air-water interface and when deposited, its LB films exhibit second-harmonic generation and asymmetric current-voltage (I-V)
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