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Merck

940801

TissueFab® PODS Growth Factor Loaded Bioink Kit

Cartilage differentiation, GelMA Vis/405 nm

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sterility

(Bioburden (fungal): < 5 CFU/mL
Bioburden (Total Aerobic): <5 CFU/ml
Endotoxin: <50 EU/ml)

form

(viscous gel)

composition

TissueFab GelMA bioink, Vis/405 nm, low endotoxin


PODS Human IGF-1, 25 µg


PODS Human TGFβ-1, 25 µg


PODS HumanTGFβ-2, 25 µg

color

colorless to pale yellow

pH

6.5-7.5

application(s)

(cartilage differentiation, cell culture, tissue engineering)

compatibility

extrusion-based 3D bioprinting

storage temp.

−20°C

General description

Rethink your bioinks with TissueFab®


About the material:

The TissueFab® PODS Growth Factor Loaded Bioink Kit, Cartilage differentiation, Vis/405 nm contains:

  • Low endotoxin GelMA-based bioink containing a visible light photoinitiator
  • Human IGF-1 PODS®
  • Human TGFβ-1 PODS®
  • Human TGFβ-2 PODS®

Printing and crosslinking parameters:

  • Suitable for extrusion-based bioprinting
  • Photoinitiator-assisted crosslinking at 405nm wavelength (Visible light)


TissueFab PODS Growth Factor Loaded Bioink kit, Cartilage differentiation, GelMA Vis/405 nm is a ready-to-use bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light.


TissueFab PODS Growth Factor Loaded Bioink kit, Cartilage differentiation, GelMA Vis/405 nm can be used with most extrusion-based bioprinters, is biodegradable, and is compatible with human mesenchymal stem cells (hMSCs). Included growth facors, IGF-1, TGFb-1, and TGFb-2, are known to play crucial roles in chondrogenic differentiation, proliferation, and repair. Their inclusion with PODS (R) delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS growth factors can promote chondrogenic differentiation of encapsulated cells. More information and a step by step protocol can be found under the "More Documents" section of this page.

Application

TissueFab PODS Growth Factor Loaded Bioink kit, Cartilage differentiation, GelMA Vis/405 nm enables the precise fabrication of chondrogenic 3D cell models and tissue constructs for research in 3D cell biology, tissue engineering, in vitro tissue models, and regenerative medicine.

Features and Benefits

Key Features and Benefits:


Each TissueFab® bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:

  • Printability and rheological properties
  • Crosslinking
  • Cell viability
  • Biocompatibility
  • Low bioburden
  • Low endotoxin
This product contains 10 ml of bioink solution and growth factors PODS® packaged separately to allow for optimization.

Legal Information

PODS is a registered trademark of Cell Guidance Systems Ltd
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany


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Kit Components Also Available Separately

Product No.
Description
SDS & Pricing

  • TissueFab® bioink  , (Gel)ma -VIS/405nm, low endotoxin
    SDS

  • Protein delivery system, Human IGF-1, PODS®
    SDS

  • Protein delivery system, Human TGF-β1, PODS®
    SDS

  • Protein delivery system, Human TGF-β2, PODS®
    SDS

Storage Class

10 - Combustible liquids



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