Key Documents

C106402

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate

Name: N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate
Brand: ALDRICH

95%

Synonym(s):

4-[2-[(Cyclohexylcarbonimidoyl)amino]ethyl]-4-methylmorpholinium p-toluenesulfonate, N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate salt, CMC, CMC metho-p-toluenesulfonate, Morpho CDI

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₂₆N₃O · C₇H₇O₃S

CAS Number:

2491-17-0

Molecular Weight:

423.57

NACRES:

NA.26

PubChem Substance ID:

329774842

UNSPSC Code:

12352111

EC Number:

219-650-3

MDL number:

MFCD00011979

Assay:

95%

Form:

crystals

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Properties

assay

95%

form

crystals

mp

113-115 °C (lit.)

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

InChI key

GBCAVSYHPPARHX-UHFFFAOYSA-M

Description

Application

Employed in a facile sequencing technique for pseudouridylate residues in RNA.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages.

Carola Schafer et al.

Malaria journal, 17(1), 370-370 (2018-10-20)

Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the unique feature of forming dormant liver stages (hypnozoites) that can reactivate weeks or months after a parasite-infected

Four newly located pseudouridylate residues in Escherichia coli 23S ribosomal RNA are all at the peptidyltransferase center: analysis by the application of a new sequencing technique.

A Bakin et al.

Biochemistry, 32(37), 9754-9762 (1993-09-21)

A new technique has been developed for the facile location of pseudouridylate (psi) residues in any RNA molecule. The method uses two known modification procedures which in combination uniquely identify U residues which have been converted into psi. The first

Mass spectrometry-based quantification of pseudouridine in RNA.

Balasubrahmanyam Addepalli et al.

Journal of the American Society for Mass Spectrometry, 22(8), 1363-1372 (2011-09-29)

Direct detection of pseudouridine (ψ), an isomer of uridine, in RNA is challenging. The most popular method requires chemical derivatization using N-cyclohexyl-N'-β-(4-methylmorpholinum ethyl) carbodiimide p-tosylate (CMCT) followed by radiolabeled primer extension mediated by reverse transcriptase. More recently, mass spectrometry (MS)-based

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