W373605
L-Tyrosine
FG
Synonym(s):
(S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine
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About This Item
Linear Formula:
4-(HO)C6H4CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
181.19
FEMA Number:
3736
UNSPSC Code:
12164502
eCl@ss:
32160406
PubChem Substance ID:
Flavis number:
17.022
EC Number:
200-460-4
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
392441
Organoleptic:
odorless
Grade:
FG
Food allergen:
no known allergens
grade
FG
reg. compliance
EU Regulation 1334/2008 & 872/2012, FDA 21 CFR 173.65
optical activity
[α]20/D −10.6°, c = 4 in 1 M HCl
mp
>300 °C (dec.) (lit.)
solubility
water: soluble 0.479 g/L at 25 °C
application(s)
flavors and fragrances
food allergen
no known allergens
organoleptic
odorless
SMILES string
N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI
1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChI key
OUYCCCASQSFEME-QMMMGPOBSA-N
General description
L-Tyrosine is an important amino acid mainly used as a dietary supplement.
L-tyrosine, an aromatic amino acid, is used common dietary supplement that has a wide range of applications in food and pharmaceutical industry. It is a precursor for preparing industrially important compounds such as 3,4-dihydroxy-L-phenylalanine (L-DOPA), melanin and p-hydroxystyrene. L-tyrosine can be synthesized by different biotechnological methods which are ecofriendly.
Other Notes
Amino acid precursor of dopamine and other catecholamines
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Christine Nicole S Santos et al.
Applied and environmental microbiology, 74(4), 1190-1197 (2007-12-25)
We present the development of a simple, high-throughput screen for identifying bacterial strains capable of L-tyrosine production. Through the introduction of a heterologous gene encoding a tyrosinase, we were able to link L-tyrosine production in Escherichia coli with the synthesis
Keisuke Saito et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7690-7695 (2013-04-20)
Using quantum mechanics/molecular mechanics calculations and the 1.9-Å crystal structure of Photosystem II [Umena Y, Kawakami K, Shen J-R, Kamiya N (2011) Nature 473(7345):55-60], we investigated the H-bonding environment of the redox-active tyrosine D (TyrD) and obtained insights that help
Hideki Hara et al.
Nature immunology, 14(12), 1247-1255 (2013-11-05)
The inflammasome adaptor ASC contributes to innate immunity through the activation of caspase-1. Here we found that signaling pathways dependent on the kinases Syk and Jnk were required for the activation of caspase-1 via the ASC-dependent inflammasomes NLRP3 and AIM2.