L7900
Sodium DL-lactate solution
synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)
Synonym(s):
DL-Lactic acid sodium salt
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About This Item
Linear Formula:
CH3CH(OH)COONa
CAS Number:
Molecular Weight:
112.06
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-772-0
Beilstein/REAXYS Number:
4332999
MDL number:
biological source
synthetic
Quality Level
product line
BioXtra
form
syrup
concentration
60 % (w/w)
technique(s)
cell culture | embryo: suitable
storage temp.
2-8°C
SMILES string
[Na+].CC(O)C([O-])=O
InChI
1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
InChI key
NGSFWBMYFKHRBD-UHFFFAOYSA-M
Application
Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
HiPS-Endothelial Cells Acquire Cardiac Endothelial Phenotype in Co-culture With hiPS-Cardiomyocytes.
Emmi Helle et al.
Frontiers in cell and developmental biology, 9, 715093-715093 (2021-08-24)
Cell-cell interactions are crucial for organ development and function. In the heart, endothelial cells engage in bidirectional communication with cardiomyocytes regulating cardiac development and growth. We aimed to elucidate the organotypic development of cardiac endothelial cells and cardiomyocyte and endothelial