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M5883

7-Methylguanosine 5′-diphosphate sodium salt

Name: 7-Methylguanosine 5&#8242;-diphosphate sodium salt
Brand: SIGMA

≥92.5%, synthetic (organic), powder

Synonym(s):

7-Methyl-gdp, m⁷GDP

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₇N₅O₁₁P₂ · xNa⁺

CAS Number:

104809-16-7

Molecular Weight:

457.23 (free acid basis)

UNSPSC Code:

41106305

PubChem Substance ID:

329818024

NACRES:

NA.51

MDL number:

MFCD00057869

Assay:

≥92.5%

Biological source:

synthetic (organic)

Form:

powder

Solubility:

water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

Storage temp.:

−20°C

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Properties

Product Name

7-Methylguanosine 5′-diphosphate sodium salt, ≥92.5%

biological source

synthetic (organic)

Quality Level

200

assay

≥92.5%

form

powder

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O)c3nc(N)nc([O-])c13

InChI

1S/C11H17N5O11P2.2Na/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(26-10)2-25-29(23,24)27-28(20,21)22;;/h3-4,6-7,10,17-18H,2H2,1H3,(H5-,12,13,14,19,20,21,22,23,24);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

VSMXIKIFPKDZJA-IDIVVRGQSA-L

Description

General description

7-Methylguanosine 5′-diphosphate (m⁷GDP) is derived when the human decapping Dcp2 enzyme cleaves the cap of the deadenylated mRNAs during the 5′–3′ mRNA decay pathway.

Application

7-Methylguanosine 5′-diphosphate sodium salt has been used as a component of the elution buffer for the purification of 5’capped RNA.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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