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341738

Sulforhodamine B, acid form

Name: Sulforhodamine B, acid form
Brand: ALDRICH

Dye content 95 %

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₃₀N₂O₇S₂

CAS Number:

2609-88-3

Molecular Weight:

558.67

NACRES:

NA.23

PubChem Substance ID:

57649121

UNSPSC Code:

12352103

EC Number:

220-025-2

MDL number:

MFCD00067690

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Properties

form

solid

Quality Level

200

composition

Dye content, 95%

mp

>300 °C (lit.)

λ_max

558 nm

SMILES string

CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S(O)(=O)=O)=[N+](/CC)CC)c1

InChI

1S/C27H30N2O7S2/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35)

InChI key

IOOMXAQUNPWDLL-UHFFFAOYSA-N

Description

General description

Sulforhodamine B (SRB) is a fluorescent protein dye. It was reported that the dye binds itself to the amino acid residues of tricholoroacetic acid fixed cells in mild basic conditions and extracts itself into the solution under mild acidic conditions.

Application

pH sensitive of SRB towards it reactivity to living cells renders it useful for scaling drug induced cytotoxicity and cell proliferations. SRB assay was used to monitor the enzymatic activity of living cells.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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