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Merck

S1429

Sodium acetate

meets USP testing specifications, anhydrous

Synonym(s):

Acetic acid sodium salt

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About This Item

Linear Formula:
CH3COONa
CAS Number:
127-09-3
Molecular Weight:
82.03
NACRES:
NA.21
PubChem Substance ID:
24899479
eCl@ss:
39021906
UNSPSC Code:
12352300
EC Number:
204-823-8
MDL number:
MFCD00012459
Beilstein/REAXYS Number:
3595639

Key Documents

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SMILES string

[Na+].CC([O-])=O

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

grade

anhydrous

agency

USP/NF, meets USP testing specifications

assay

99-101% dry basis

form

solid

autoignition temp.

1112 °F

pH

8.5-9.9 (25 °C, 246 g/L)

pKa 

4.76 (acetic acid)

mp

>300 °C (dec.) (lit.)

solubility

soluble 246 g/L at 20 °C (completely)

application(s)

pharmaceutical (small molecule)

Quality Level

200

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General description

Sodium acetate (SA) exhibits antimicrobial and antioxidant properties. It is used as an exchange-fluid buffer in hemodialysis. SA acts as an a alkalinizing agent and its continuous intravenous (IV) infusion causes salicylate intoxication.

Application

Sodium acetate (SA) has been used to increase hepatic acetyl- coenzyme A in caloric restricted rats.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL2888
SLCC8154
SLBZ7505
SLBX1607
SLBT9729

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Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon
Sallam KI, et al.
Food Control, 18(5), 566-575 (2007)
Mechanisms by which a very-low-calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
Perry RJ, et al.
Cell Metabolism, 27(1), 210-217 (2018)
Enhancement of in-vitro human interleukin-1 production by sodium acetate
Bingel M, et al.
Lancet, 329(8523), 14-16 (1987)
Sodium Acetate as an Alkalinizing Agent for Salicylate Intoxication: A Case Report
Groke SF, et al.
Journal of Clinical Toxicology (2015)
Amanda P De Souza et al.
Journal of experimental botany, 66(14), 4351-4365 (2015-04-25)
The production of bioenergy from grasses has been developing quickly during the last decade, with Miscanthus being among the most important choices for production of bioethanol. However, one of the key barriers to producing bioethanol is the lack of information
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