T0254
L-Tryptophan
≥98% (HPLC)
Synonym(s):
(S)-2-Amino-3-(3-indolyl)propionic acid, L-α-Amino-3-indolepropionic acid
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About This Item
Empirical Formula (Hill Notation):
C11H12N2O2
CAS Number:
Molecular Weight:
204.23
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-795-6
MDL number:
Beilstein/REAXYS Number:
86197
Product Name
L-Tryptophan, reagent grade, ≥98% (HPLC)
grade
reagent grade
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to off-white
mp
280-285 °C (dec.) (lit.)
solubility
0.5 M HCl: 50 mg/mL
application(s)
cell analysis
SMILES string
N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChI key
QIVBCDIJIAJPQS-VIFPVBQESA-N
Gene Information
human ... TDO2(6999), TPH1(7166), TPH2(121278)
Application
L-tryptophan has been used for the isolation of bone marrow–derived neutrophils. It has also been used to identify the use of Raman microscopy as a tool to study the network of neurons in pathologically normal retina.
Biochem/physiol Actions
Tryptophan (Trp) is a heterocyclic, essential amino acid associated with growth, reproduction and immunity. Increased availability of tryptophan is necessary for the regulation of mood, cognition and behavior. The uptake of tryptophan by the brain depends on the plasma ratio of Trp to all of the other large neutral amino acids. Higher the ratio, greater is the Trp uptake.
Other Notes
Amino acid precursor of serotonin and melatonin
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Raman microscopy of porcine inner retinal layers from the area centralis
J. Renwick
Molecular Vision (2007)
Tryptophan Catabolism Restricts IFN-??Expressing Neutrophils and Clostridium difficile Immunopathology
Mohamad El-Zaatari
Journal of Immunology (2014)
Effects of tryptophan loading on human cognition, mood, and sleep.
Neuroscience and Biobehavioral Reviews, 34(3) (2010)