Skip to Content
Merck

T6399

Trichloroacetic acid

ACS reagent grade, ≥99.0%

Synonym(s):

TCA

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
Cl3CCOOH
CAS Number:
76-03-9
Molecular Weight:
163.39
NACRES:
NA.21
PubChem Substance ID:
24900373
UNSPSC Code:
12352100
EC Number:
200-927-2
MDL number:
MFCD00004177
Beilstein/REAXYS Number:
970119
Assay:
≥99.0%
Form:
crystalline
Grade:
ACS reagent

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Trichloroacetic acid, ACS reagent, ≥99.0%

Quality Level

200

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

SMILES string

OC(=O)C(Cl)(Cl)Cl

grade

ACS reagent

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99.0%

form

crystalline

impurities

Substances darkened by sulfuric acid, passes test, ≤0.01% insoluble matter

ign. residue

≤0.03%

refractive index

n20/D 1.62 (lit.)

pH

(1 at 81.7 g/l at 25 °C)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

H2O: 1 g/10 mL

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.002%, nitrate (NO3-): ≤0.002%, phosphate (PO43-): ≤5 ppm, sulfate (SO42-): ≤0.02%

cation traces

Fe: ≤0.001%, heavy metals (as Pb): ≤0.002%

functional group

carboxylic acid, chloro

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

  • Trichloroacetic acid has been used for the precipitation of sLRP (soluble circulating low density lipoprotein receptor-related protein-1) isolated from plasma.
  • It has been used for the extraction of ascorbic acid from plant samples. It has also been used for the preparation of ascorbate standards for ascorbate assay.
  • It has been used for the precipitation of IMAC (immobilized metal ion affinity chromatography)-isolated phosphoproteins.
Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy.

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H314,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
STBK6833
STBK6151
STBK4799
STBJ3637
STBK4669

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Measurement of reduced, oxidized and total ascorbate content in plants.
Gillespie KM and Ainsworth EA
Nature Protocols, 2, 871-871 (2007)
Casein Kinase 2 (CK2)-mediated Phosphorylation of Hsp90? as a Novel Mechanism of Rifampin-induced MDR1 Expression.
Kim SW et al.
The Journal of Biological Chemistry, 290, 17029-17029 (2015)
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-? is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Sagare AP et al.
Journal of Alzheimer'S Disease, 24, 25-25 (2011)
Seokjo Kang et al.
Journal of Alzheimer's disease : JAD, 70(3), 667-680 (2019-07-01)
Increased levels of total tau (t-tau) and hyperphosphorylated tau (p-tau) proteins in the cerebrospinal fluid of Alzheimer's disease (AD) patients are well documented and strongly correlate with AD pathology. Recent studies have further shown that human tau can be released
Ying Wang et al.
Diabetes, 63(8), 2643-2655 (2014-03-13)
After diabetes, the heart has a singular reliance on fatty acid (FA) for energy production, which is achieved by increased coronary lipoprotein lipase (LPL) that breaks down circulating triglycerides. Coronary LPL originates from cardiomyocytes, and to translocate to the vascular
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service