46945
Fluorescein isothiocyanate–dextran
average mol wt 70,000, (FITC:Glucose = 1:250)
Synonym(s):
FITC-Dextran 70, FITC–Dextran
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About This Item
biological source
synthetic
Quality Level
conjugate
FITC conjugate
form
powder
mol wt
average mol wt 70,000
composition
(FITC:Glucose = 1:250)
concentration
90-100 % (w/w) (TRITC DEXTRAN)
extent of labeling
~0.004 mol/mol FITC glucose
color
light orange to very dark orange, light yellow to very dark yellow
solubility
H2O: 50 mg/mL, hazy, orange to very deep orange
fluorescence
λex 492 nm; λem 518 nm in ethanol
application(s)
cell analysis
storage temp.
2-8°C
Application
Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.
Fluorescein isothiocyanate–dextran (FITC-Dextran 70) is use as a fluorescent probe to study cell processes such as cell permeability, phagocytosis and endocytosis and to study mechanisms of biomolecular delivery. FITC-Dextran 70 may be used to study the capacity, selectivity and efficiency of encapsulation and release by drug delivery vehicles.
Other Notes
Internalisation of FITC and FITC-dextran by suspension cultured plant cells; In the study of fluid pinocytosis in leukocytes
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signalword
Warning
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
hcodes
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