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Merck

84959

L-Serine

≥99.5% (NT), suitable for cell culture, BioUltra

Synonym(s):

(S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
105.09
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-274-3
MDL number:
Beilstein/REAXYS Number:
1721404
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Product Name

L-Serine, BioUltra, ≥99.5% (NT)

product line

BioUltra

Quality Level

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D +13.5±0.5°, c = 5% in 5 M HCl

technique(s)

cell culture | mammalian: suitable

impurities

insoluble matter, passes filter test, ≤0.3% foreign amino acids

ign. residue

≤0.1% (as SO4)

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

222 °C (dec.) (lit.)

solubility

1 M HCl: 0.5 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤50 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, NH4+: ≤100 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

λ

0.5 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.05

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

Application


  • Effect of SlSAHH2 on metabolites in over-expressed and wild-type tomato fruit.: Research focused on the metabolite variations in genetically modified tomatoes, including the impact of L-Serine in metabolic engineering to enhance nutritional values and stress resistance (Yang et al., 2024).

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

Other Notes

Synthesis of labels for protonation studies by Fourier Transform infrared methods; Stabilizes mung bean nuclease at pH values below seven; Amino acid spacing in isotachophoresis on polyacrylamide gel - a critical evaluation; Growth requirement of various microorganisms


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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CRC Handbook of Microbiology, 4, 1-1 (1974)
Bacteriorhodopsin: fourier transform infrared methods for studies of protonation of carboxyl groups.
G Dollinger et al.
Methods in enzymology, 127, 649-662 (1986-01-01)
Theory of protein solubility.
T Arakawa et al.
Methods in enzymology, 114, 49-77 (1985-01-01)