Skip to Content
Merck

M1195

Metolazone

≥98% (HPLC), solid

Synonym(s):

7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C16H16ClN3O3S
CAS Number:
17560-51-9
Molecular Weight:
365.83
NACRES:
NA.77
PubChem Substance ID:
24724532
UNSPSC Code:
12352200
EC Number:
241-539-3
MDL number:
MFCD00069304
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)

InChI key

AQCHWTWZEMGIFD-UHFFFAOYSA-N

SMILES string

CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(N)(=O)=O

assay

≥98% (HPLC)

form

solid

color

white

solubility

DMSO: >5 mg/mL

Quality Level

100

Gene Information

human ... SLC12A1(6557), SLC12A3(6559)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

Inhibitor of thiazide-sensitive Na+-Cl- cotransporter; antihypertensive; moderate "loop" diuretic.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
025M4752V
102M4734V
117K47002
117K47001
117K4700

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

[Therapy edema: secondary effect without effect!].
B Truniger
Schweizerische medizinische Wochenschrift, 129(46), 1808-1808 (1999-12-22)
S C Hebert et al.
Kidney international, 49(6), 1638-1641 (1996-06-01)
Recently the molecular identification of the major electroneutral sodium-potassium-chloride entry mechanisms present on apical membranes of distal nephron segments of the mammalian kidney, on basolateral membranes of many non-renal epithelial cells and on certain non-epithelial tissues has been achieved. These
Lynda Blue et al.
European journal of heart failure, 7(3), 351-361 (2005-02-19)
This article examines the emerging role of the heart failure nurse and the responsibilities and educational and training requirements surrounding such a role. There may be variations in the role and its responsibilities in different health care settings. However the
A Monroy et al.
American journal of physiology. Renal physiology, 279(1), F161-F169 (2000-07-15)
The thiazide-sensitive Na(+)-Cl(-) cotransporter (TSC) is the major pathway for salt reabsorption in the apical membrane of the mammalian distal convoluted tubule. When expressed in Xenopus laevis oocytes, rat TSC exhibits high affinity for both cotransported ions, with the Michaelis-Menten
Puja K Puri et al.
Journal of cutaneous pathology, 35(12), 1134-1137 (2008-08-30)
We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service