135828
Benzamide
99%
Sinónimos:
Benzoic acid amide
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Acerca de este artículo
Fórmula lineal:
C6H5CONH2
Número CAS:
Peso molecular:
121.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-227-7
Beilstein/REAXYS Number:
385876
MDL number:
Assay:
99%
Servicio técnico
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99%
mp
125-128 °C (lit.)
solubility
ethanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to light yellow
functional group
amide, phenyl
SMILES string
NC(=O)c1ccccc1
InChI
1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)
InChI key
KXDAEFPNCMNJSK-UHFFFAOYSA-N
Gene Information
human ... PARP1(142)
General description
Benzamide on radioiodination by different labeling procedures results in large-scale production of radioiodinated benzamides having potential therapeutic application for patients with metastatic malignant melanoma.
Benzamide is used as a building block in organic synthesis for the preparation of various biologically active compounds.
Benzamide is used as a building block in organic synthesis for the preparation of various biologically active compounds.
Application
Benzamide was used to study the mechanism of photocatalytic decomposition of aqueous solution of acetic acid, acetamide and acetonitrile in the presence of semiconductors. It was used to develop a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.
Biochem/physiol Actions
Inhibits poly(ADP-ribose) polymerase (PARP).
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Muta. 2
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 1
flash_point_f
356.0 °F - closed cup
flash_point_c
180 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Walter Mier et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(1), 9-14 (2013-11-28)
The performance of cytotoxic drugs is defined by their selectivity of uptake and action in tumor tissue. Recent clinical responses achieved by treating metastatic malignant melanoma with therapeutic modalities based on gene expression profiling showed that malignant melanoma is amenable
Photocatalytic Decompositions of Carboxylic Acid Derivatives by Semiconductors.
Park KH and Kim JH.
Bull. Korean Chem. Soc., 12(4), 439-439 (1991)
Willian G Birolli et al.
Pesticide biochemistry and physiology, 156, 129-137 (2019-04-28)
Chiral pesticides have been used in agriculture, including (±)-lambda-cyhalothrin ((±)-LC), which is a pyrethroid insecticide widely employed on crops for protection against different types of insects. However, enantioselectivity is poorly studied in biodegradation processes. Therefore, the (±)-LC enantioselective biodegradation by