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Merck

283215

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

Sinónimos:

PAA HCl, PAH

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Fórmula lineal:
[CH2CH(CH2NH2 · HCl)]n
Número CAS:
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
415-050-2
MDL number:
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Nombre del producto

Poly(allylamine hydrochloride), average Mw ~17,500 (GPC vs. PEG std.)

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

SMILES string

Cl.NCC=C

form

solid

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

Quality Level

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Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Jingguo Li et al.
Chemistry, an Asian journal, 8(2), 385-391 (2012-12-12)
Multimodal imaging and simultaneous therapy is highly desirable because it can provide complementary information from each imaging modality for accurate diagnosis and, at the same time, afford an imaging-guided focused tumor therapy. In this study, indocyanine green (ICG), a near-infrared
Yiyao Liu et al.
Expert opinion on drug delivery, 9(10), 1197-1207 (2012-09-27)
Technologies to increase tissue vascularity are critically important to the fields of tissue engineering and cardiovascular medicine. Angiogenic factors, like VEGF, have been widely investigated to induce vascular endothelial cell proliferation and angiogenesis for establishing a vascular network. However, effective
L Minati et al.
International journal of pharmaceutics, 438(1-2), 45-52 (2012-09-11)
Gold nanoparticles functionalized with doxorubicin and stabilized with multilayers of degradable polyelectrolyte were allowed to age in aqueous medium in vitro in order to show the possibility of drug release in cellular environment. The chemico-physical characteristics of the nanoparticles are
Ya Wang et al.
Macromolecular bioscience, 12(10), 1321-1325 (2012-09-12)
Fluorescent-magnetic-biotargeting multifunctional microcapsules (FMBMMs) are designed and fabricated via layer-by-layer assembly. It is found that the arginine-glycine-aspartate-modified FMBMMs were capable of sensitively detecting and efficiently isolating approximately 80% target cancer cells within 20 min. More importantly, FMBMMs present a general
Bing Wang et al.
Macromolecular bioscience, 12(11), 1534-1545 (2012-09-26)
The mechanism of the cellular uptake of polyelectrolyte microcapsules and its influences on the functions and toxicity of human SMCs are explored. The covalently assembled poly(allylamine hydrochloride)/glutaraldehyde microcapsules are easily ingested by SMCs mainly through macropinosis and caveolae-mediated endocytosis pathways.

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