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Merck

M90003

trans,trans-Muconic acid

95%

Sinónimos:

trans,trans-1,3-Butadiene-1,4-dicarboxylic acid, trans,trans-2,4-Hexadienedioic acid

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Acerca de este artículo

Fórmula lineal:
HO2CCH=CHCH=CHCO2H
Número CAS:
Peso molecular:
142.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
222-724-8
Beilstein/REAXYS Number:
1722248
MDL number:
Assay:
95%
Form:
powder
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InChI key

TXXHDPDFNKHHGW-ZPUQHVIOSA-N

InChI

1S/C6H6O4/c7-5(8)3-1-2-4-6(9)10/h1-4H,(H,7,8)(H,9,10)/b3-1+,4-2+

SMILES string

OC(=O)\C=C\C=C\C(O)=O

assay

95%

form

powder

bp

320 °C (lit.)

mp

290 °C (dec.) (lit.)

Quality Level

General description

trans,trans-Muconic acid is a polyunsaturated dicarboxylic acid characterized by its conjugated double bonds and reactive dicarboxylic groups. It serves primarily as a key precursor to monomers in the synthesis of polyamides and polyesters.

Application

trans,trans-Muconic acid can be used as a:
  • Reactant to produce aromatic monomers via Diels-Aldercycloaddition.
  • Biomarker for benzene exposure.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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G Scherer et al.
Journal of chromatography. B, Biomedical sciences and applications, 717(1-2), 179-199 (1998-12-01)
Benzene is an important industrial chemical and, due to its occurrence in mineral oil and its formation in many combustion processes, a widespread environmental pollutant. Since benzene is hematoxic and has been classified as a human carcinogen, monitoring and control
Nancy B Hopf et al.
International archives of occupational and environmental health, 85(3), 261-271 (2011-06-15)
Characterize ethylbenzene and xylene air concentrations, and explore the biological exposure markers (urinary t,t-muconic acid (t,t-MA) and unmetabolized toluene) among petroleum workers offshore. Offshore workers have increased health risks due to simultaneous exposures to several hydrocarbons present in crude oil.
Francesco Marchetti et al.
Environmental health perspectives, 120(2), 229-234 (2011-11-17)
Benzene is an industrial chemical that causes blood disorders, including acute myeloid leukemia. We previously reported that occupational exposures near the U.S. Occupational Safety and Health Administration permissible exposure limit (8 hr) of 1 ppm was associated with sperm aneuploidy.
Sirirat Chanvaivit et al.
Mutation research, 626(1-2), 79-87 (2006-11-11)
Exposure to benzene can cause DNA damage and the subsequent development of cancer. In this study, study subjects were 31 laboratory workers at a petrochemical factory and 31 gasoline service attendants. Control subjects were 34 workers from a mail sorting
Stephen S Hecht
Carcinogenesis, 23(6), 907-922 (2002-06-26)
Measurement of human urinary carcinogen metabolites is a practical approach for obtaining important information about tobacco and cancer. This review presents currently available methods and evaluates their utility. Carcinogens and their metabolites and related compounds that have been quantified in

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