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Merck

W294004

1,2-Propanediol

≥99.5% (GC), FCC, FG

Sinónimos:

1,2-Propanediol, Propylene glycol

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Fórmula lineal:
CH3CH(OH)CH2OH
Número CAS:
Peso molecular:
76.09
PubChem Substance ID:
UNSPSC Code:
12164502
Council of Europe no.:
4212
FEMA Number:
2940
NACRES:
NA.21
EC Number:
200-338-0
MDL number:
Beilstein/REAXYS Number:
1340498
E Number:
E 1520
Organoleptic:
odorless
Grade:
FG, Fragrance grade, Halal, Kosher
Biological source:
synthetic
Agency:
follows IFRA guidelines
Food allergen:
no known allergens
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InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

SMILES string

CC(O)CO

biological source

synthetic

grade

FG, Fragrance grade, Halal, Kosher

agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009, FCC, FDA 21 CFR 175.300, FDA 21 CFR 175.320, FDA 21 CFR 176.180, FDA 21 CFR 176.210, FDA 21 CFR 184.1666, EU Regulation 1333/2008 & 178/2002

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

viscous liquid

autoignition temp.

779 °F

expl. lim.

12.5 %

refractive index

n20/D 1.432 (lit.)

Quality Level

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

odorless

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General description

Propylene glycol is an aliphatic dihydric alcohol with a wide range of applications in the food industry such as an anticaking agent, antioxidant, humectant, flavoring agent, emulsifier, stabilizer, thickener etc.

Application


  • Fatally impaired glucose digestion by propylene glycol in Aedes aegypti (Diptera: Culicidae) and co-formulation with terpenoids for enhancing attractive toxic sugar baits.: This study explores the application of propylene glycol in impairing glucose digestion in mosquitoes, offering a novel approach to vector control through enhanced toxic sugar baits. The synergy with terpenoids broadens its impact, marking significant progress in pest management strategies (Maes et al., 2024).

  • Null cross-modal effects of olfactory training on visual, auditory or olfactory working memory in 6- to 9-year-old children.: This neuroscientific study utilizes propylene glycol in olfactory training exercises, investigating its potential to influence cross-modal sensory processing. Despite null findings, it provides a critical assessment of sensory integration therapies (Pieniak et al., 2024).

  • Propylene glycol toxicity in an adolescent secondary to chronic cornstarch ingestion.: This medical case study addresses the risks associated with excessive propylene glycol intake, highlighting its potential toxic effects. The study serves as a crucial reminder of the need for regulatory scrutiny and public awareness regarding chemical additives in food products (Downey et al., 2024).

Clase de almacenamiento

10 - Combustible liquids

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

wgk

WGK 1

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup


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Visite la Librería de documentos

Handbook of Preservatives, 508-508 (2004)
Encyclopedia of Food and Color Additives, 2, 2347-2347 (1997)
Bahareh Eftekharzadeh et al.
Nature communications, 10(1), 3562-3562 (2019-08-10)
Molecular chaperones such as Hsp40 and Hsp70 hold the androgen receptor (AR) in an inactive conformation. They are released in the presence of androgens, enabling transactivation and causing the receptor to become aggregation-prone. Here we show that these molecular chaperones
R S Rajasenan et al.
Toxicology and applied pharmacology, 135(1), 89-99 (1995-11-01)
Engrafting components of human immune systems in severe combined immunodeficient (SCID) mice has been utilized to investigate the pathogenesis of several human autoimmune diseases and may provide a model for studying idiosyncratic drug toxicity. The purpose of this investigation was
G A Reichard et al.
Diabetes, 35(6), 668-674 (1986-06-01)
Plasma acetone turnover rates were measured with the primed continuous infusion of 2-[14C]acetone in patients with moderate to severe diabetic ketoacidosis. Plasma acetone turnover rates ranged from 1.52 to 15.9 mumol X kg-1 X min-1 (108-1038 mumol X 1.73 m-2

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