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Merck

W308307

Triethyl citrate

≥99%, FCC, FG

Sinónimos:

Ethyl citrate

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Fórmula lineal:
HOC(COOC2H5)(CH2COOC2H5)2
Número CAS:
Peso molecular:
276.28
FEMA Number:
3083
Council of Europe no.:
11762
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
9.512
EC Number:
201-070-7
NACRES:
NA.21
MDL number:
Beilstein/REAXYS Number:
1801199
Organoleptic:
odorless
Grade:
FG, Halal, Kosher
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens
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SMILES string

CCOC(=O)CC(O)(CC(=O)OCC)C(=O)OCC

InChI

1S/C12H20O7/c1-4-17-9(13)7-12(16,11(15)19-6-3)8-10(14)18-5-2/h16H,4-8H2,1-3H3

InChI key

DOOTYTYQINUNNV-UHFFFAOYSA-N

biological source

synthetic

grade

FG, Halal, Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 872/2012, FCC, FDA 21 CFR 117, FDA 21 CFR 175.300, FDA 21 CFR 175.320, FDA 21 CFR 181.27, FDA 21 CFR 184.1911

vapor density

9.7 (vs air)

vapor pressure

1 mmHg ( 107 °C)

assay

≥99%

refractive index

n20/D 1.442 (lit.)

bp

235 °C/150 mmHg (lit.)

density

1.14 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

Quality Level

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Categorías relacionadas

General description

Triethyl citrate can be used as a plasticizer and sequestrant in the food industry.

Application


  • Cosmetically Approved Short-Chain Alcohol/Triethyl Citrate/Water Surfactant-Free Microemulsions and Potential Application to Transdermal Penetration of α-Arbutin.: This study investigates the formulation of surfactant-free microemulsions using triethyl citrate, exploring its potential in enhancing the transdermal penetration of α-arbutin. The results suggest significant improvement in skin delivery, highlighting the cosmetic and pharmaceutical potential of triethyl citrate (Zhang et al., 2024).

  • Understanding the Interaction of Thermal, Rheological, and Mechanical Parameters Critical for the Processability of Polyvinyl Alcohol-Based Systems during Hot Melt Extrusion.: This research delves into the role of triethyl citrate as a plasticizer in polyvinyl alcohol-based systems, essential for optimizing hot melt extrusion processes. The findings emphasize the importance of precise thermal and mechanical control in pharmaceutical applications (Hess et al., 2024).

  • The effect of additives on the biodegradation of polyhydroxyalkanoate (PHA) in marine field trials.: Triethyl citrate is evaluated as an additive to improve the biodegradation of polyhydroxyalkanoates in marine environments. This study presents its efficacy in enhancing environmental sustainability through accelerated degradation (Read et al., 2024).

  • In-situ forming PLGA implants: Towards less toxic solvents.: Investigating the use of triethyl citrate as a less toxic solvent alternative in PLGA implants, this paper demonstrates its potential in reducing toxicity while maintaining implant efficacy, beneficial for pharmaceutical applications (Ramos et al., 2024).

  • Influence of Low-Molecular-Weight Esters on Melt Spinning and Structure of Poly(lactic acid) Fibers.: This article explores the impact of triethyl citrate on the properties of poly(lactic acid) fibers, highlighting its role in enhancing fiber structure and processability for industrial applications (Gzyra-Jagieła et al., 2024).

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

311.0 °F - closed cup

flash_point_c

155 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Certificados de análisis (COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What amount is there in the SAMPLE size of Product W308307, Triethyl citrate?

    Sample package size contains 10 grams.

  6. How do I reconstitute Product W308307, Triethyl citrate?

    You can reconstitute Triethyl citrate in water at a concentration of 65 g/l. (27500 product pink database)

  7. What grade is Product W308307, Triethyl citrate, and how do I get the Certificates on this product?

    The product W308307 is classified under the following grades: Food grade (FG), FCC, HALAL, Kosher and NI grade. The Certificates are available from our website or contact techserv@sial.com or call 1-800-325-5832.

  8. What is the meaning of FCC?

    FCC refers to Food Chemical Codex. To products of this category testings done are based on the Government Food Grade products guidelines.(F&F group).

  9. Is there any alcohol present in Product W308307, Triethyl citrate?

    The final product will have alcohol present. It will be less than 0.05 wt %. (ipi)

  10. What is the form of Product W308307, Triethyl citrate, liquid or solid? How can I find that?

    The product W308307 is in a liquid form and this information is found in the specification sheet.

  11. How do I convert the solid unit package to liquid volume for Product W308307, Triethyl citrate?

    If you divide the package size by the density of Triethyl citrate (1.14 g/ml), you can get the volume amount in that package. Example: 1000 gm/1.14 g/ml which is 877.19 ml.

  12. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Dictionary of Food ingredients, 144-144 (2013)
Food Additives, 682-682 (1999)
M R Abbaspour et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 68(3), 747-759 (2007-11-06)
One challenge in tableting of sustained-release multiparticulates is maintaining the desired drug release after compaction. The aim of this study was to design sustained-release ibuprofen tablets which upon oral ingestion rapidly disintegrate into sustained-release pellets in which the integrity of
Soravoot Rujivipat et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 81(1), 223-229 (2012-01-25)
Enteric polymers such as cellulose esters (cellulose acetate phthalate, hydroxypropylmethylcellulose acetate succinate) and methacrylic acid-acrylate copolymers (Eudragit® L100-55 and S100) are quite brittle in the dry state and thus not suitable as pellet coatings for compression into tablets. The objective
Kakuyou Ogawa et al.
Biological & pharmaceutical bulletin, 37(9), 1559-1563 (2014-09-02)
Zerumbone 1 is an 11-membered cyclic sesquiterpene obtained from the rhizomes of Zingiber zerumbet SMITH (Zingiberaceae). In this study, we investigated the structure-activity relationship of 1, α-humulene (2), tetrahydrozerumbone stereoisomers (3-5), and tetrahydrozerumbone derivatives (6-9). The oxygen-containing functional groups and

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