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Merck

07-140

Anti-STAT2 Antibody

Upstate®, from rabbit

Sinónimos:

Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
EMSA, ICC, IP, WB
Citations:
25

Documentos clave

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse

manufacturer/tradename

Upstate®

technique(s)

electrophoretic mobility shift assay: suitable, immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

NM_005419

UniProt accession no.

P52630

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... STAT2(6773)

General description

130kDa

Immunogen

GST-fusion protein corresponding to residues 672-925 of murine STAT2

Application

Anti-STAT2 Antibody is a Rabbit Polyclonal Antibody for detection of STAT2 also known as Signal Transducer & Activator of Transcription 2 & has been tested in EMSA, IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Biochem/physiol Actions

STAT2

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Affinity Chromatography

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.
Zhu Guo, Sanjay Garg, Karen M Hill, Lakshmi Jayashankar, Myesha R Mooney, Mary Hoelscher et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
Connie C Qiu et al.
Oncoimmunology, 10(1), 1860477-1860477 (2021-01-19)
STAT2 is a central component of the ISGF3 transcriptional complex downstream of type I interferon (IFN-I) signaling. The significance of in vivo IFN-I/STAT1 signals in cDCs is well-established in the generation of antitumor cytotoxic T cell (CTL) responses. However, the role
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
Zurney, J; Kobayashi, T; Holm, GH; Dermody, TS; Sherry, B
Journal of virology null
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.
Lagor, WR; Fields, DW; Bauer, RC; Crawford, A; Abt, MC; Artis, D; Wherry, EJ; Rader, DJ
Atherosclerosis null
M Matsumoto et al.
Biological chemistry, 380(6), 699-703 (1999-08-03)
The interferon-stimulated gene factor 3 (ISGF3) transcription factor has been extensively studied in the context of the type I interferon (IFN-alpha/beta)-mediated antiviral response; it consists of the major DNA-binding component p48, and the signal transducers and activators of transcription (Stat)1
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