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Merck

07-614

Anti-Surfactant Protein B Antibody

serum, Upstate®

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
Species reactivity:
mouse, human
Citations:
10
Technique(s):
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
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Nombre del producto

Anti-Surfactant Protein B Antibody, serum, Upstate®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Sftpd(20390)

Analysis Note

routinely evaluated by immunoblot on human bronchiolar lavage fluid.

Application

Anti-Surfactant Protein B Antibody is an antibody against Surfactant Protein B for use in IH & WB.
Research Category
Metabolism
Research Sub Category
Ion & Transport Channels

Biochem/physiol Actions

Surfactant Protein B

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

8kDa

Immunogen

Purified human surfactant protein B

Physical form

Serum
rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Ralph Epaud et al.
American journal of respiratory cell and molecular biology, 28(3), 373-378 (2003-02-21)
Transgenic mice, in which the level of surfactant protein (SP)-B mature peptide varied 5.6-fold between SP-B(+/-) and SP-B-overexpressing lines (SP-B+/+/+), were used to test the hypothesis that SP-B protects against endotoxin-induced lung inflammation. Intratracheal administration of endotoxin resulted in significantly
Yan Liu et al.
Molecular reproduction and development, 84(8), 668-674 (2017-05-18)
Respiratory distress is a major cause of mortality in cloned neonatal animals, but its pathogenesis remains poorly understood. Here, we used necropsy and histology procedures to evaluate the lungs of cloned neonatal bovines dying of respiratory distress, finding incomplete lung
Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.
Gregory, T J, et al.
The Journal of Clinical Investigation, 88, 1976-1981 (1991)
L M Nogee et al.
American journal of respiratory and critical care medicine, 161(3 Pt 1), 973-981 (2000-03-11)
Inability to produce surfactant protein B (SP-B) causes fatal neonatal respiratory disease. A frame-shift mutation (121ins2) is the predominant but not exclusive cause of disease. To determine the range of mechanisms responsible for SP-B deficiency, both alleles from 32 affected
Eileen L Whiteman et al.
Molecular and cellular biology, 34(1), 43-56 (2013-10-30)
First identified in Drosophila, the Crumbs (Crb) proteins are important in epithelial polarity, apical membrane formation, and tight junction (TJ) assembly. The conserved Crb intracellular region includes a FERM (band 4.1/ezrin/radixin/moesin) binding domain (FBD) whose mammalian binding partners are not

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SKUGTIN
07-61404053252272226

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