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Merck

MPTMAG-49K

MILLIPLEX® Mouse Pituitary Panel

Configurable Mouse Pituitary 7-Plex Panel

Sinónimos:

MPTMAG-49K product info, endocrine biomarker multiplex kit, mouse endocrine research tool, mouse growth and metabolism panel, mouse hormone assay overview, mouse pituitary hormone panel, multiplex hormone profiling kit, neuroendocrine marker panel mouse, pituitary function biomarker listing, reproductive biology product sheet

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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species reactivity

mouse

Quality Level

200

assay range

accuracy: 96-101%, standard curve range: 12.2-50,000 pg/mL
(TSH), standard curve range: 122-500,000 pg/mL
(Prolactin), standard curve range: 2.4-10,000 pg/mL
(ACTH), standard curve range: 2.4-10,000 pg/mL
(BDNF), standard curve range: 24.4-100,000 pg/mL
(FSH), standard curve range: 4.9-20,000 pg/mL
(GH), standard curve range: 4.9-20,000 pg/mL
(LH), inter-assay cv: <20%
intra-assay cv: <15%

technique(s)

multiplexing: suitable

input

tissue/cellular lysate
plasma
culture supernatant(s)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Categorías relacionadas

General description

The pituitary gland, often referred to as the “master gland,” regulates multiple endocrine functions through the secretion of key hormones. This panel—ACTH, BDNF, FSH, GH, LH, Prolactin, and TSH—captures essential indicators of adrenal, thyroid, gonadal, and neuroendocrine activity. The MILLIPLEX® Mouse Pituitary Panel enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting research in reproductive biology, metabolism, and endocrine disorders.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in mouse serum, plasma, or cell/tissue culture supernatants.

Analytes Included: ACTH, BDNF, FSH, GH, LH, Prolactin, TSH

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Targets key pituitary hormones involved in endocrine and neuroendocrine regulation
  • Includes 7 analytes relevant to metabolism, growth, reproduction, and neuronal function
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in reproductive biology, endocrine disorders, and neuroendocrine signaling
Benefits:

  • Provides a comprehensive profile of pituitary hormone biomarkers in mouse models
  • Supports investigation of endocrine function and hormonal regulation mechanisms
  • Facilitates evaluation of therapeutic interventions and endocrine toxicity
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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D H Loh et al.
Journal of biological rhythms, 29(5), 355-369 (2014-09-26)
The female reproductive cycle is gated by the circadian timing system and may be vulnerable to disruptions in the circadian system. Prior work suggests that vasoactive intestinal peptide (VIP)-expressing neurons in the suprachiasmatic nucleus (SCN) are one pathway by which
Typhanie Dumontet et al.
JCI insight, 3(2) (2018-01-26)
The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher primates increase prepubertal androgen secretion, is unknown. Using cell-fate mapping and gene deletion studies in
An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.
Pitetti, JL; Calvel, P; Zimmermann, C; Conne, B; Papaioannou, MD; Aubry, F; Cederroth et al.
Molecular Endocrinology null
Tomohiro Terasaka et al.
Endocrinology, 160(8), 1999-2014 (2019-06-13)
Gonadotropin secretion, which is elicited by GnRH stimulation of the anterior pituitary gonadotropes, is a critical feature of reproductive control and the maintenance of fertility. In addition, activation of the GnRH receptor (GnRHR) regulates transcription and translation of multiple factors
Thomas Blum et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(30), 15236-15243 (2019-07-10)
Dopamine neurons of the hypothalamic arcuate nucleus (ARC) tonically inhibit the release of the protein hormone prolactin from lactotropic cells in the anterior pituitary gland and thus play a central role in prolactin homeostasis of the body. Prolactin, in turn
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SKUGTIN
MPTMAG-49K-0304053252829222
MPTMAG-49K-0704053252829055
MPTMAG-49K-0504053252829031
MPTMAG-49K-0604053252829048
MPTMAG-49K-0104053252829208
MPTMAG-49K-0204053252829215
MPTMAG-49K-0404053252829024

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