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Merck

27301

Salicylic acid

99.5-100.5% (calc. to the dried substance), meets analytical specification of Ph. Eur., BP, USP

Sinónimos:

2-Hydroxybenzoic acid

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Fórmula lineal:
2-(HO)C6H4CO2H
Número CAS:
69-72-7
Peso molecular:
138.12
NACRES:
NA.21
PubChem Substance ID:
24856524
UNSPSC Code:
12352100
EC Number:
200-712-3
MDL number:
MFCD00002439
Beilstein/REAXYS Number:
774890
Assay:
99.5-100.5% (calc. to the dried substance)

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Nombre del producto

Salicylic acid, meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

SMILES string

OC(=O)c1ccccc1O

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

assay

99.5-100.5% (calc. to the dried substance)

quality

meets analytical specification of Ph. Eur., BP, USP

impurities

residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤0.2% related subst. (HPLC)

ign. residue

≤0.05% (as SO4)

loss

≤0.3% loss on drying

bp

211 °C (lit.)

mp

158-161 °C (lit.), 158-161 °C

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤200 mg/kg

suitability

complies for appearance of solution, complies for identity

application(s)

pharmaceutical (small molecule)

functional group

carboxylic acid

Quality Level

200

Gene Information

human ... ALB(213), PTPN1(5770)

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Categorías relacionadas

Application

  • Salinity stress management in agriculture: A study demonstrated the application of salicylic acid in ameliorating salinity stress in barley, revealing its potential to enhance crop resilience to saline environments, thereby contributing to sustainable agricultural practices (Hanif et al., 2024).
  • Enhanced pharmaceutical gel performance: Research on nitrocellulose for prolonged permeation of Levofloxacin HCl-Salicylic Acid In Situ gel emphasized its utility in enhancing drug delivery systems, particularly in treating bacterial infections with improved efficacy (Khaing et al., 2024).
  • Biotechnological production of withanolides: Salicylic acid was applied as an elicitor in the hairy root culture of Withania somnifera, significantly boosting the production of withanolides and phenolic acids, vital for pharmaceutical applications due to their therapeutic properties (Halder and Ghosh, 2024).

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCG9763
BCCF1182
BCCD5667
BCCC6264
BCCB7855

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Salicylic acid activates nitric oxide synthesis in Arabidopsis.
Zottini M, et al.
Journal of Experimental Botany, 58(6), 1397-1405 (2007)
Rapid colorimetric determination of nitrate in plant tissue by nitration of salicylic acid1.
Cataldo DA, et al.
Communications in Soil Science and Plant Analysis, 6(1), 71-80 (1975)
E Benfeldt et al.
Acta dermato-venereologica, 79(5), 338-342 (1999-09-24)
Our aim was to simultaneously investigate 2 techniques for in vivo sampling of peripheral compartment pharmacokinetics after systemic administration of acetylsalicylic acid. Ten volunteers were given 2 g acetylsalicylic acid orally. Blood samples and dialysates from 4 microdialysis probes inserted
S Zaugg et al.
Journal of chromatography. B, Biomedical sciences and applications, 752(1), 17-31 (2001-03-20)
Acetylsalicylic acid (Aspirin) is rapidly metabolized to salicylic acid (salicylate) and other compounds, including gentisic acid and salicyluric acid. Monitoring of salicylate and its metabolites is of toxicological, pharmacological and biomedical interest. Three capillary electrophoresis (CE) methods featuring alkaline aqueous
Yunlong Du et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7946-7951 (2013-04-25)
Removal of cargos from the cell surface via endocytosis is an efficient mechanism to regulate activities of plasma membrane (PM)-resident proteins, such as receptors or transporters. Salicylic acid (SA) is an important plant hormone that is traditionally associated with pathogen
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