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Merck

34001

Ceftiofur

VETRANAL®, analytical standard

Sinónimos:

3-[(2-Furylcarbonyl)thio]methyl]-7-[2-(2-amino-4-thiazolyl)-2-(methoxyiminoacetamido)-3-cephem-4-carboxylic acid

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Fórmula empírica (notación de Hill):
C19H17N5O7S3
Número CAS:
80370-57-6
Peso molecular:
523.56
NACRES:
NA.24
PubChem Substance ID:
329754745
UNSPSC Code:
41116107
MDL number:
MFCD00864953

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InChI

1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16?/m1/s1

SMILES string

CO\N=C(/C(=O)N[C@H]1C2SCC(CSC(=O)c3ccco3)=C(N2C1=O)C(O)=O)c4csc(N)n4

InChI key

ZBHXIWJRIFEVQY-FITYNHDMSA-N

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

Quality Level

100

Categorías relacionadas

General description

Ceftiofur is a third-generation cephalosporin antibiotic, which is commonly used in veterinary medicine for the treatment of respiratory diseases and bacterial infections in farm animals.

Application

Ceftiofur has been used as an analytical reference standard for the determination of the analyte in:
  • Milk samples using receptor binding assays such as Betastar Combo, SNAP, and Twinsensor tests.
  • Environmental water samples using capillary electrophoresis.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCD2522
BCBS8768V
BCBS8758V

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Can I store stock solutions of Product 34001, Ceftiofur?

    One publication cites storage of 1 mg/mL stock solutions of Product 34001, Ceftiofur, at -70 °C in methanol for 1 month.  De Baere, S., et al., High-performance liquid chromatographic-UV detection analysis of ceftiofur and its active metabolite desfuroylceftiofur in horse plasma and synovial fluid after regional intravenous perfusion and systemic intravenous injection of ceftiofur sodium.  Analytica Chimica Acta, 512 (1), 75-84 (2004).

  6. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Fabian M Kausche et al.
Veterinary therapeutics : research in applied veterinary medicine, 4(1), 83-93 (2003-05-21)
Seven well-controlled studies conducted under multiple management conditions demonstrated that ceftiofur, a late-generation veterinary parenteral cephalosporin, is effective for the treatment of bovine foot rot in beef and dairy cattle. Two preliminary dosage titration studies using a challenge model compared
Determination of ceftiofur and its metabolite desfuroylceftiofur in bovine serum and milk by ion-paired liquid chromatography.
Tyczkowska LK, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 614(1), 123-134 (1993)
Alessio Lorusso et al.
The Journal of general virology, 95(Pt 12), 2618-2626 (2014-08-17)
Interactions between the viral surface glycoprotein haemagglutinin (HA) and the corresponding receptors on host cells is one important aspect of influenza virus infection. Mutations in HA have been described to affect pathogenicity, antigenicity and the transmission of influenza viruses. Here
Anton Kaufmann et al.
Rapid communications in mass spectrometry : RCM, 31(22), 1915-1926 (2017-09-07)
The linear intrascan and interscan dynamic ranges of mass spectrometers are important in metabolome and residue analysis. A large linear dynamic range is mandatory if both low- and high-abundance ions have to be detected and quantitated in heavy matrix samples.
Improving the sensitivity of the determination of ceftiofur by capillary electrophoresis in environmental water samples: In-line solid phase extraction and sample stacking techniques.
Puig P, et al.
Analytica Chimica Acta, 587(2), 208-215 (2007)
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