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Merck

BP421

17α-etinilestradiol

British Pharmacopoeia (BP) Assay Standard

Sinónimos:

17α-etinil-1,3,5(10)-estratrieno-3,17β-diol, 19-Nor-1,3,5(10),17α-pregnatrien-20-ino-3,17-diol, Etinilestradiol

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Fórmula empírica (notación de Hill):
C20H24O2
Número CAS:
57-63-6
Peso molecular:
296.40
EC Number:
200-342-2
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
2419975
MDL number:
MFCD00003690

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InChI key

BFPYWIDHMRZLRN-SLHNCBLASA-N

InChI

1S/C20H24O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,5,7,12,16-18,21-22H,4,6,8-11H2,2H3/t16-,17-,18+,19+,20+/m1/s1

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@@]3(O)C#C)[C@]1([H])CCc4cc(O)ccc24

grade

pharmaceutical primary standard

API family

ethinyl estradiol

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

182-183 °C (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... ESR1(2099)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ethinylestradiol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Co-cyprindiol Tablets
  • Levonorgestrel Tablets
  • Norgestrel Tablets
  • Levonorgestrel and Ethinylestradiol Tablets
  • Ethinylestradiol Tablets

    • Other Notes

    Sales restrictions may apply.

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 1 - Carc. 2 - Repr. 1A

    Clase de almacenamiento

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

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    Certificados de análisis (COA)

    Lot/Batch Number

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    Andrew M Kaunitz et al.
    Obstetrics and gynecology, 123(2 Pt 1), 295-303 (2014-01-10)
    To compare a new low-dose levonorgestrel and ethinyl estradiol contraceptive patch (Patch) with a combination oral contraceptive (Pill; 100 micrograms levonorgestrel, 20 micrograms ethinyl estradiol) regarding efficacy, safety, compliance, and unscheduled uterine bleeding. Women (17-40 years; body mass index 16-60)
    Matteo Morotti et al.
    European journal of obstetrics, gynecology, and reproductive biology, 183, 178-182 (2014-12-03)
    To evaluate the effect of a desogestrel progestogen-only pill (POP) compared to continuous combined oral contraception (COC) on migraine patterns in women with migraine without aura. A retrospective analysis of prospective headache charts from migrainous women who used the POP
    Marie Louise Wissing et al.
    Journal of ovarian research, 7, 110-110 (2014-11-30)
    Corona radiata cells (CRCs) refer to the fraction of cumulus cells just adjacent to the oocyte. The CRCs are closely connected to the oocyte throughout maturation and their gene expression profiles might reflect oocyte quality. Polycystic ovary syndrome (PCOS) is
    Christoph Kapitza et al.
    Journal of clinical pharmacology, 55(5), 497-504 (2014-12-06)
    The effect of semaglutide, a once-weekly human glucagon-like peptide-1 (GLP-1) analog in development for type 2 diabetes (T2D), on the bioavailability of a combined oral contraceptive was investigated. Postmenopausal women with T2D (n = 43) on diet/exercise ± metformin received ethinylestradiol (0.03 mg)/levonorgestrel (0.15 mg) once
    Gregory Brazzola et al.
    Evolutionary applications, 7(9), 1084-1093 (2015-01-02)
    The evolutionary potential of natural populations to adapt to anthropogenic threats critically depends on whether there exists additive genetic variation for tolerance to the threat. A major problem for water-dwelling organisms is chemical pollution, and among the most common pollutants
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