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Merck

M1800000

17α-Methyltestosterone

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

17α-Methyltestosterone, 17α-Methyl-4-androsten-17β-ol-3-one, 17β-Hydroxy-17α-methyl-4-androsten-3-one, Mesterone, Methyltestosterone

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Fórmula empírica (notación de Hill):
C20H30O2
Número CAS:
58-18-4
Peso molecular:
302.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329817711
MDL number:
MFCD00003655
Beilstein/REAXYS Number:
2057425

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InChI

1S/C20H30O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h12,15-17,22H,4-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

SMILES string

C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI key

GCKMFJBGXUYNAG-HLXURNFRSA-N

grade

pharmaceutical primary standard

API family

methyltestosterone

manufacturer/tradename

EDQM

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

162-168 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... AR(367)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Methyltestosterone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 1B - Repr. 2

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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Sushant Kumar Verma et al.
PloS one, 9(7), e101439-e101439 (2014-07-09)
The present study was carried out to analyze the differences in the activity of hormone stanniocalcin (STC) between male and female fishes of Mastacembelus armatus during their gonadal cycle. A large variation in nuclear diameter of cells of corpuscles of
Eric H Phillips et al.
Clinical therapeutics, 25(12), 3027-3043 (2004-01-30)
The use of hormone-replacement therapy (HRT) to treat menopausal symptoms has been influenced over the years by various safety concerns. These concerns include endometrial cancer, breast cancer, and cardiovascular disease, and have altered how HRT is prescribed. Evaluating postmarketing surveillance
Jingzhu Wang et al.
Analytical and bioanalytical chemistry, 406(24), 6061-6067 (2014-08-12)
Progesterone (PROG) is a naturally occurring progestagen, which has been used to prevent preterm birth, control persistent anovulatory bleeding, and treat premenstrual syndrome in clinical practices. Studies on the metabolism of PROG have demonstrated that PROG is the precursor of
Jingzhu Wang et al.
Analytica chimica acta, 852, 146-152 (2014-12-03)
Isotope ratio mass spectrometry (IRMS) is applied to confirm testosterone (T) abuse by determining the carbon isotope ratios (δ(13)C value). However, (13)C labeled standards can be used to control the δ(13)C value and produce manipulated T which cannot be detected
Shuuji Mawaribuchi et al.
Endocrinology, 155(10), 3996-4005 (2014-07-23)
The African clawed frog, Xenopus laevis, has a ZZ/ZW-type sex-determination system. We previously reported that a W-linked gene, Dm-W, can determine development as a female. However, the mechanisms of early sex differentiation remain unclear. We used microarrays to screen for
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