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PHR1097

L-Tirosina

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

3-(4-Hidroxifenil)-L-alanina, Ácido (S)-2-Amino-3-(4-hidroxifenil)propiónico

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Fórmula lineal:
4-(HO)C6H4CH2CH(NH2)CO2H
Número CAS:
60-18-4
Peso molecular:
181.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823119
EC Number:
200-460-4
Beilstein/REAXYS Number:
392441
MDL number:
MFCD00002606
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Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. T2900000, traceable to USP 1705006

API family

tyrosine

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

>300 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

L-Tyrosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by a liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Aminoácido precursor de la dopamina y otras catecolaminas
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7163 in the slot below. This is an example certificate only and may not be the lot that you receive.

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Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 1

Certificados de análisis (COA)

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Proceedings of the National Academy of Sciences of the United States of America, 110(19), 7690-7695 (2013-04-20)
Using quantum mechanics/molecular mechanics calculations and the 1.9-Å crystal structure of Photosystem II [Umena Y, Kawakami K, Shen J-R, Kamiya N (2011) Nature 473(7345):55-60], we investigated the H-bonding environment of the redox-active tyrosine D (TyrD) and obtained insights that help
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