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Merck

PHR1561

Tetrahidrofuran

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Oxolano, Óxido de butileno, Óxido de tetrametileno

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Fórmula empírica (notación de Hill):
C4H8O
Número CAS:
109-99-9
Peso molecular:
72.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823470
EC Number:
203-726-8
Beilstein/REAXYS Number:
102391
MDL number:
MFCD00005356

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Nombre del producto

Tetrahidrofuran, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

WYURNTSHIVDZCO-UHFFFAOYSA-N

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2

SMILES string

C1CCOC1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1601770

vapor density

2.5 (vs air)

vapor pressure

114 mmHg ( 15 °C)
143 mmHg ( 20 °C)

CofA

current certificate can be downloaded

autoignition temp.

610 °F

expl. lim.

1.8-11.8 %

packaging

ampule of 3x1.2 mL each

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.407 (lit.)

bp

65-67 °C (lit.)

mp

−108 °C (lit.)

density

0.889 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Tetrahydrofuran is a saturated cyclic ether with a potential use as a biofuel. It is used for the manufacture of polyurethanes.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0275 in the slot below. This is an example certificate only and may not be the lot that you receive.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

EUH019

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 1

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Szycher's Handbook of Polyurethanes (1999)
Fabrice Giusti et al.
The Journal of membrane biology, 247(9-10), 909-924 (2014-03-22)
Amphipols are short amphipathic polymers that can substitute for detergents at the hydrophobic surface of membrane proteins (MPs), keeping them soluble in the absence of detergents while stabilizing them. The most widely used amphipol, known as A8-35, is comprised of
Lucie Nováková et al.
Analytica chimica acta, 853, 647-659 (2014-12-04)
The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, namely UHPLC-MS/MS and
Gyan P Mishra et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(2), 397-405 (2014-06-17)
Biodegradable poly(ethyleneglycol)-poly(valerolactone)-poly(ethyleneglycol) [PEG-PVL-PEG] copolymers were synthesized through ring opening polymerization of δ-valerolactone (VL) followed by the coupling of monomethoxy poly(ethyleneglycol-poly(valerolactone) (mPEG-PVL) with hexamethylene diisocyanate (HDI). The copolymers were characterized by (1)H NMR, FT-IR, and GPC. Block copolymers of PEG and
N Frančič et al.
The Analyst, 139(12), 3127-3136 (2014-05-03)
In this work we demonstrate the efficient immobilization of histidine 6-tagged organophosphate hydrolase (His6-OPH), an organophosphate-degrading enzyme, on mesoporous titania thin films. This permits the use of the biocatalyst films as efficient tools in the detection/detoxification of paraoxon. His6-OPH was
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