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Merck

S7920

Sodium fluoride

BioXtra, ≥99%

Sinónimos:

NaF, Natrium fluoride, Sodium monoflouride

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Fórmula lineal:
NaF
Número CAS:
Peso molecular:
41.99
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-667-8
MDL number:
Assay:
≥99%
Solubility:
H2O: 1 M, clear, colorless
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vapor pressure

1.4 mmHg ( 0 °C)

Quality Segment

product line

BioXtra

assay

≥99%

impurities

≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter

mp

993 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%

cation traces

Al: ≤0.001%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.003%, K: ≤0.02%, Mg: ≤0.0005%, NH4+: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%

SMILES string

[F-].[Na+]

InChI

1S/FH.Na/h1H;/q;+1/p-1

InChI key

PUZPDOWCWNUUKD-UHFFFAOYSA-M

Application

Sodium fluoride has been used:
  • as a source of fluoride ions, to analyse its impact on spermatogenesis and capacitation in vitro
  • as an additive in the extraction buffer for the isolation of nuclei, cytoplasmic and nuclear proteins
  • as a component of lysis buffer for the lysis of human ovarian adenocarcinoma OVCAR3 cells

Biochem/physiol Actions

Sodium fluoride (NaF) prevents dental caries, by catalysing the diffusion of calcium and phosphate and remineralizes the lesions. Fluoride affects spermatogenesis and capacitation process in the female reproductive tract. Fluoride induces oxidative stress, DNA damage in ovary ultimately affects the development of oocytes. Fluoride supplementation enhances bone mineral density. 18F-NaF is a radiotracer used in positron emission tomography (PET) to identify atherosclerotic lesions and other cardiac plaques.


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pictograms

Skull and crossbones

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Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

supp_hazards

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



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