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Merck

320552

Tolueno

ACS reagent, ≥99.5%

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Fórmula lineal:
C6H5CH3
Número CAS:
Peso molecular:
92.14
UNSPSC Code:
12352002
NACRES:
NA.21
PubChem Substance ID:
EC Number:
203-625-9
Beilstein/REAXYS Number:
635760
MDL number:
Assay:
≥99.5%
Grade:
ACS reagent
Bp:
110-111 °C (lit.)
Vapor pressure:
22 mmHg ( 20 °C), 26 mmHg ( 25 °C)
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grade

ACS reagent

Quality Level

agency

suitable for EPA 1613

vapor density

3.2 (vs air)

vapor pressure

22 mmHg ( 20 °C), 26 mmHg ( 25 °C)

assay

≥99.5%

form

liquid

autoignition temp.

997 °F

expl. lim.

7 %

dilution

(for analytical testing)

impurities

H2SO4, passes test (darkened), ≤0.003% S compounds, ≤0.03% water

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n/D 1.496 (lit.)

bp

110-111 °C (lit.)

mp

-93 °C (lit.)

density

0.865 g/mL at 25 °C (lit.)

SMILES string

Cc1ccccc1

InChI

1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3

InChI key

YXFVVABEGXRONW-UHFFFAOYSA-N

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General description

Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application

Toluene can be used as a solvent:
  • To synthesize azines from alcohols and hydrazine hydrate.
  • In the lipase-catalyzed synthesis of epoxy-functionalized polyesters via polycondensation.

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 3

flash_point_f

39.9 °F - closed cup

flash_point_c

4.4 °C - closed cup


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Marina Shalaeva et al.
Journal of medicinal chemistry, 56(12), 4870-4879 (2013-05-29)
This study demonstrates that ΔlogP(oct-tol) (difference between logP(octanol) and logP(toluene)) describes compounds propensity to form intramolecular hydrogen bonds (IMHB) and may be considered a privileged molecular descriptor for use in drug discovery and for prediction of IMHB in drug candidates.
Liang Guo et al.
Journal of chromatography. A, 1286, 9-15 (2013-03-19)
For the first time, a novel one-step sample preparation method that combines microwave assisted extraction and solvent bar microextraction (MAE-SBME) with analysis by gas chromatography-mass spectrometry (GC-MS), was developed for the fast and efficient determination of polycyclic aromatic hydrocarbons (PAHs)
Christopher M Filley et al.
Journal of neuropathology and experimental neurology, 63(1), 1-12 (2004-01-30)
In recent decades the organic solvent toluene (methylbenzene) has emerged as one of the best-studied neurotoxins. Long-term and intense exposure to toluene vapors in humans who abuse spray paint and related substances has led to the recognition that toluene has
Murat Yücel et al.
Neuroscience and biobehavioral reviews, 32(5), 910-926 (2008-05-06)
Organic solvent abuse is associated with increased risk for serious medical, neurological, and neuropsychological impairments. While animal research suggests that exposure to organic solvents (especially toluene) may be neurotoxic, much less is known about the consequences of long-term exposure in
Perrine Hoet et al.
Critical reviews in toxicology, 38(2), 127-170 (2008-02-09)
Noise is the most common preventable cause of irreversible sensorineural hearing loss. During recent years, the results of experimental and human investigations have raised the level of concern about the potential ototoxicity of chemical agents and their interaction with noise.

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