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Merck

45999

Methyl acetate

suitable for HPLC, ≥99.8%

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Fórmula lineal:
CH3COOCH3
Número CAS:
Peso molecular:
74.08
UNSPSC Code:
12190000
NACRES:
NA.01
PubChem Substance ID:
EC Number:
201-185-2
Beilstein/REAXYS Number:
1736662
MDL number:
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InChI key

KXKVLQRXCPHEJC-UHFFFAOYSA-N

InChI

1S/C3H6O2/c1-3(4)5-2/h1-2H3

SMILES string

COC(C)=O

vapor density

2.55 (vs air)

vapor pressure

165 mmHg ( 20 °C)

assay

≥99.8% (GC), ≥99.8%

form

liquid

autoignition temp.

936 °F

shelf life

limited shelf life, expiry date on the label

expl. lim.

16 %

technique(s)

HPLC: suitable

impurities

≤0.05% water

evapn. residue

≤0.001%

refractive index

n20/D 1.361 (lit.), n20/D 1.362

bp

57-58 °C (lit.)

mp

−98 °C (lit.)

density

0.934 g/mL at 25 °C

solvent strength ε (Al2O3)

0.60

λ

1 cm path, H2O reference

UV absorption

λ: 255 nm Amax: 1.0, λ: 275 nm Amax: 0.1, λ: 300 nm Amax: 0.01

Quality Level

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Application

  • Agglomeration of celecoxib by quasi-emulsion solvent diffusion method without stabilizer: effect of good solvent.: This research explored the agglomeration of celecoxib using the quasi-emulsion solvent diffusion method, highlighting the role of methyl acetate as a good solvent to improve particle size and distribution without the need for stabilizers (Maghsoodi & Nokhodchi, 2018).
  • Formulation and in vitro evaluation of ketoprofen in palm oil esters nanoemulsion for topical delivery.: The formulation and evaluation of ketoprofen in a nanoemulsion system for topical delivery were examined, with methyl acetate used as a solvent to enhance solubility and stability of the active ingredient (Sakeena et al., 2010).
  • Preparation of surfactant-free nanoparticles of methacrylic acid copolymers used for film coating.: This paper presented a method for preparing surfactant-free nanoparticles using methyl acetate as a solvent, emphasizing its role in the formation of uniform nanoparticle dispersions for coating applications (Nguyen et al., 2006).

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 1

flash_point_f

8.6 °F - closed cup

flash_point_c

-13 °C - closed cup


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The Journal of chemical physics, 138(4), 044319-044319 (2013-02-08)
Highly correlated ab initio calculations (CCSD(T)) are used to compute gas phase spectroscopic parameters of three isotopologues of the methyl acetate (CH(3)COOCH(3), CD(3)COOCH(3), and CH(3)COOCD(3)), searching to help experimental assignments and astrophysical detections. The molecule shows two conformers cis and
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Recent calorimetric measurements of the solvation enthalpies of some dipeptide analogs confirm our earlier prediction that the principle of group additivity is not valid for the interaction of the peptide group with water. We examine the consequences for understanding the

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