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Merck

31388

Dextrano from Leuconostoc spp.

Mr ~6,000

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Fórmula lineal:
(C6H10O5)n
Número CAS:
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-677-5
MDL number:
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Nombre del producto

Dextrano from Leuconostoc spp., Mr ~6,000

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

biological source

(Leuconostoc spp)

form

powder

mol wt

Mr ~6,000

color

white

mp

483  °C ((901 °F ))

solubility

water: 1.5 g/10 mL, colorless to faintly yellow

storage temp.

room temp

Quality Level

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Application

Dextran from Leuconostoc spp. has been used:
  • for the glycation of caseinate to investigate the influence of an increase in carbohydrate chain length compared to glucose
  • for the mass calibration of matrix-assisted laser desorption ionization-time of flight mass spectroscopy (MALDI-TOF) for the characterization of silver nanoparticles (AgNPs)
  • as a non-toxic stabilizer to assess the in vivo administration of tungsten trioxide(WO3) nanoparticles

Biochem/physiol Actions

Dextran is used as a drug, particularly as a blood plasma volume expander. It is also useful as an adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Sephadex is a cross-linked dextran that is commonly used for the separation and purification of protein. In the food industry, dextran is applicable as a thickener for jam and ice cream. It hinders the crystallization of sugar and augments moisture retention. This preserves the flavor and appearance of several food items.

General description

Dextran is a branched glucan composed of linear α(1→6) linked glucose units and α (1→3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components. Low molecular weight dextrans are often preferred versus high molecular weight dextrans due to their different viscosities, aggregation and permeation properties.
Dextran is an extracellular bacterial polymer of D-glucopyranose. It mostly comprises α-(1→6) linkage in the main chain and a variable number of α-(1→2), α-(1→3), α-(1→4) branched linkages.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

ppe

Eyeshields, Gloves, type N95 (US)


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Thomas Rath et al.
Nephron. Clinical practice, 114(1), c81-c88 (2009-11-06)
Intravenous iron supplementation is a basic principle in the therapy of haemodialysis (HD) patients with renal anaemia. In the Iron Dextran in Renal Anaemia (IDIRA) study, we analysed the efficacy of a therapy with low-molecular-weight iron dextran (LMW-ID) in stable
Eugen Sisu et al.
Rapid communications in mass spectrometry : RCM, 20(2), 209-218 (2005-12-15)
A combined methodology for obtaining at the preparative scale and characterization by nanoelectrospray ionization (nanoESI) quadrupole time-of-flight (QTOF) mass spectrometry (MS) and tandem MS (MS/MS) of linear polysaccharides modified at the reducing end is presented. Two polydisperse maltodextrins (1000 and
R J Stenekes et al.
Biomaterials, 22(13), 1891-1898 (2001-06-09)
In this paper, a novel method is presented for the preparation of dextran hydrogels and microspheres, based on crystallization. Although dextrans are known to be well soluble in water, precipitation was observed in concentrated aqueous solutions of low molecular weight
Diego Delgado et al.
Human gene therapy, 23(4), 345-355 (2012-02-03)
The goal of the present study was to analyze the potential application of nonviral vectors based on solid lipid nanoparticles (SLN) for the treatment of ocular diseases by gene therapy, specifically X-linked juvenile retinoschisis (XLRS). Vectors were prepared with SLN
Yuichi Ozaki et al.
Circulation journal : official journal of the Japanese Circulation Society, 76(4), 922-927 (2012-02-04)
Although an intracoronary frequency-domain optical coherence tomography (FD-OCT) system overcomes several limitations of the time-domain OCT (TD-OCT) system, the former requires injection of contrast media for image acquisition. The increased total amount of contrast media for FD-OCT image acquisition may

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