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Merck

61743

N-Lauroilsarcosina sodium salt

BioUltra, Molecular Biology, ≥99.0% (HPLC)

Sinónimos:

N-Dodecanoil-N-metilglicina sodium salt, Sarkosyl NL

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Fórmula lineal:
CH3(CH2)10CON(CH3)CH2COONa
Número CAS:
137-16-6
Peso molecular:
293.38
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57651862
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
MFCD00042728

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Nombre del producto

N-Lauroilsarcosina sodium salt, BioUltra, Molecular Biology, ≥99.0% (HPLC)

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

grade

Molecular Biology

description

anionic

product line

BioUltra

assay

≥99.0% (HPLC)

form

powder

mol wt

micellar avg mol wt 600
average mol wt 600

aggregation number

2

impurities

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

loss

≤1% loss on drying, 110 °C

pH

7.0-9.0 (25 °C, 1 M in H2O)

CMC

14.6 mM (20-25°C)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06

application(s)

sample preservation

Quality Level

200

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Other Notes

Tensioactivo aniónico.

Application

N-Lauroylsarcosine sodium salt has been used as a component:

  • of nuclease stop mix, embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
  • of proteinase K solution for the heat denaturation of genomic DNA
  • of 10% (w/v) sarcosyl/0.5 M ethylenediaminetetraacetic acid (EDTA) solution to prepare EDTA-sarcosyl-proteinase (ESP) buffer
  • in the hybridization buffer for in situ hybridization histochemistry
  • in the embryo extract buffer to dissociate nonspecifically bound proteins from chromatin
  • in proteinase K solution to inactivate the enzymes

General description

The N-lauroylsarcosine sodium salt is applicable for processes that require tight control of elemental content. This product aids in the solubilization and separation of membrane proteins, glycoproteins, and the isolation of RNA and plasmids. N-lauroylsarcosine sodium salt serves as an antifoaming supplement or as a component of a lysing buffer of bacteria or other cells. It indicates the paramagnetic anisotropy sign change in the micelle mesophase. N-lauroylsarcosine sodium salt inhibits hexokinase and the bacterial flora of human saliva/gut at 0.25%. It also exhibits fungistatic activity in aqueous dispersion (1%). N-lauroylsarcosine (LS) is an anionic surfactant with protein denaturant potency that is structurally similar to sodium lauryl sulfate (SLS). It can inactivate herpes simplex virus (HSV) infectivity in vitro. It is used as a microbicide in topical vaginal formulations to block the transmission of HSV, human immunodeficiency virus type 1 (HIV-1), and possibly other pathogens causing sexually transmitted diseases (STDs).

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

512.6 °F - closed cup

flash_point_c

267 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCG4842
BCCF4825
BCCF0374
BCCC9502
BCCC0765

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