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A2093

Aspirin

Name: Aspirin
Brand: SIGMA

meets USP testing specifications

Sinónimos:

Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin

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Fórmula lineal:

2-(CH₃CO₂)C₆H₄CO₂H

Número CAS:

50-78-2

Peso molecular:

180.16

UNSPSC Code:

12352106

NACRES:

NA.21

PubChem Substance ID:

24890623

EC Number:

200-064-1

Beilstein/REAXYS Number:

779271

MDL number:

MFCD00002430

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Propiedades

Quality Segment

200

agency

USP/NF, meets USP testing specifications

form

powder or crystals

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Gene Information

human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)

Descripción

General description

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

Application

Aspirin has been used:

as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
to evaluate cell viability of BV-2 microglial cell line
in morphogenesis assay

Biochem/physiol Actions

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.