G9885
α1-Acid Glycoprotein from human plasma
≥99% (agarose gel electrophoresis)
Sinónimos:
AGP, Orosomucoid
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Form:
powder
Assay:
≥99% (agarose gel electrophoresis)
Biological source:
human plasma
Servicio técnico
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Permítanos ayudarlebiological source
human plasma
assay
≥99% (agarose gel electrophoresis)
form
powder
technique(s)
ELISA: suitable
impurities
HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ORM1(5004)
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Application
α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
Biochem/physiol Actions
α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
General description
α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.
Preparation Note
Purified from Cohn Fraction VI
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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In Vitro Effect of alpha1-Acid Glycoprotein on the Anti?Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors
Lazdins J K, et al.
The Journal of Infectious Diseases, 175(5), 1063-1070 (1997)
Hendrik Grootaert et al.
Glycobiology, 30(9), 735-745 (2020-03-10)
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living cells, and in mammals it is involved in a wide range of biological processes including leukocyte trafficking, histo-blood group antigenicity and antibody effector functions. The
Effect of once weekly administration of mifepristone on ovarian function in normal women
Chen X and Xiao B
Contraception, 56(3), 175-180 (1997)
Protein adsorption onto auto-assembled polyelectrolyte films
Ladam G, et al.
Langmuir, 17(3), 878-882 (2001)
Alpha-1-acid glycoprotein
Fournier T, et al.
Biochimica et Biophysica Acta, 1482(1-2), 157-171 (2000)
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