Saltar al contenido
Merck

Documentos clave

Ver Toda la documentación

N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

Sinónimos:

Fungicidin, Mycostatin

para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas

Acerca de este artículo

Número CAS:
1400-61-9
UNSPSC Code:
12352207
PubChem Substance ID:
24897511
NACRES:
NA.76
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

Nombre del producto

Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture

product line

BioReagent

Quality Segment

200

form

suspension

concentration

10,000 unit/mL in DPBS

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

yellow

antibiotic activity spectrum

fungi, yeast

mode of action

cell membrane | interferes

shipped in

dry ice

storage temp.

−20°C

SMILES string

C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O

InChI

1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI key

VQOXZBDYSJBXMA-QEKUPDCNSA-N

General description

Chemical structure: polyene

Application

Nystatin suspension has been used:
  • to inhibit caveolin-mediated endocytosis
  • as a component of Eagle′s minimum essential medium (EMEM)
  • to enumerate lactic acid bacteria (LAB)
  • in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.
This product is recommended for use in cell culture applications at 24 mL/L.

Biochem/physiol Actions

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

Preparation Note

It is 0.1μ filtered and cell culture tested.

Other Notes

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Disclaimer

This product is stable at 37°C for three days.

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documentos section.

Si necesita más asistencia, póngase en contacto con Atención al cliente

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos