P4562
Piruvato sódico
powder, BioXtra, suitable for mouse embryo cell culture
Sinónimos:
αÁcido α-cetopropiónico sodium salt, Ácido 2-oxopropanoico sodium salt, Ácido pirúvico sodium salt
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Fórmula lineal:
CH3COCOONa
Número CAS:
Peso molecular:
110.04
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
204-024-4
Beilstein/REAXYS Number:
3568341
MDL number:
Assay:
≥99%
Form:
powder
Servicio técnico
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BioXtra
Quality Segment
assay
≥99%
form
powder
technique(s)
cell culture | embryo: suitable
mp
>300 °C (lit.)
solubility
H2O: 100 mg/mL
storage temp.
2-8°C
SMILES string
[Na+].CC(=O)C([O-])=O
InChI
1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
InChI key
DAEPDZWVDSPTHF-UHFFFAOYSA-M
General description
Pyruvate, the end-product of the glycolysis pathway, is the anion of pyruvic acid.
Application
Sodium pyruvate has been used:
- as a supplement in Ca2+ + N-Tris(hydroxymethil)methyl-2-aminoethanesulfonic acid (TES)–NaCl medium for sperm incubation
- as a supplement in TCM-199 hepes modification solution for cumulus-oocytes complexes (COC′s) culture
- as a supplement in Dulbecco′s modified Eagle medium (DMEM) to culture mouse primary hepatocytes (MPHs) and also to intraperitoneally inject fasted mice for glucose production assessment
Biochem/physiol Actions
Sodium pyruvate is mainly used as a constituent in culture broth and media. It exhibits anti-oxidation and anti-inflammatory properties. Hence sodium pyruvate is considered a possible therapy for allergic rhinitis. Sodium pyruvate might also be a new approach treating lactic acidosis.
Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. Sodium pyruvate attenuates oxidative stress in vitro. The 100 mM solution should be diluted at 1:100 for most cell culture applications. This product has been qualified for use in mouse embryo cultures.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1B
Clase de almacenamiento
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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