U1752
Uridine 5′-monophosphate
≥98%, natural (organic), powder
Sinónimos:
U 5′-P, UMP, Uridylic acid
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Fórmula empírica (notación de Hill):
C9H13N2O9P
Número CAS:
Peso molecular:
324.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-408-0
MDL number:
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Permítanos ayudarleNombre del producto
Uridine 5′-monophosphate, ≥98%
InChI key
DJJCXFVJDGTHFX-UHFFFAOYSA-N
InChI
1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)
SMILES string
OC1C(O)C(OC1COP(O)(O)=O)N2C=CC(=O)NC2=O
biological source
natural (organic)
assay
≥98%
form
powder
solubility
H2O: soluble 50 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
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Categorías relacionadas
Application
Uridine 5′-monophosphate has been used as a component in isotonic E3 medium for isotonic reconstitution experiments to study its effects on the basal cell response or epithelial cell migration to the wound in the isotonic medium.
Biochem/physiol Actions
Uridine 5′-monophosphate (UMP) is a nucleotide monomer in RNA. It contains the nucleobase uracil along with the ribose sugar and a phosphate group. UMP dietary supplementation enhances neurotransmitter release and neurite outgrowth and also promotes membrane phosphatide production in adult rats. Oral supplementation of DHA, co-administered with UMP, in adult gerbils shows an increase in dendritic spines and neuronal membrane synthesis. It suggests a strategy for the treatment of cognitive disorders resulting from synapse loss.
General description
Uridine 5′-monophosphate acts as a precursor for all pyrimidine nucleotides.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lei Wang et al.
Journal of molecular neuroscience : MN, 27(1), 137-145 (2005-08-02)
Membrane phospholipids like phosphatidylcholine (PC) are required for cellular growth and repair, and specifically for synaptic function. PC synthesis is controlled by cellular levels of its precursor, cytidine-5'-diphosphate choline (CDP-choline), which is produced from cytidine triphosphate (CTP) and phosphocholine. In
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