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Merck

X4002

Xanthine

≥99%, synthetic (organic), powder

Sinónimos:

2,6-Dihydroxypurine

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Fórmula empírica (notación de Hill):
C5H4N4O2
Número CAS:
69-89-6
Peso molecular:
152.11
NACRES:
NA.51
PubChem Substance ID:
24902144
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
MFCD00078453
Beilstein/REAXYS Number:
8733

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Nombre del producto

Xanthine, BioUltra, ≥99%

InChI key

LRFVTYWOQMYALW-UHFFFAOYSA-N

InChI

1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)

SMILES string

O=C1NC(=O)c2nc[nH]c2N1

biological source

synthetic (organic)

product line

BioUltra

assay

≥99%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

solubility

1 M NaOH: 0.1 M, clear, colorless to light yellow

anion traces

sulfate (SO42-): <0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

Quality Level

200

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Application

Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
  • yeast culture
  • human cell line culture
  • recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli

Biochem/physiol Actions

Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.

Features and Benefits

  • Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
  • Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)

General description

Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
  • Guanine deamination by guanine deaminase
  • Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
SLCK5817
SLCJ4094
SLCB7555
SLBB5664V
077K53071V

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 9(11), 995-1003 (1995-08-01)
Xanthine oxidase and xanthine dehydrogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfusion damage in
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