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Fórmula empírica (notación de Hill):
C17H21NO · HCl
Número CAS:
Peso molecular:
291.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Servicio técnico
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pharmaceutical primary standard
API family
diphenhydramine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2
InChI
1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChI key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Diphenhydramine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Acetaminophen, Diphenhydramine Hydrochloride, and Pseudoephedrine Hydrochloride Tablets
- Dimenhydrinate
- Dimenhydrinate Tablets
- Diphenhydramine and Phenylephrine Hydrochlorides Tablets
- Diphenhydramine and Pseudoephedrine Capsules
- Diphenhydramine Hydrochloride
- Diphenhydramine Hydrochloride and Ibuprofen Capsules
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Olabisi Oduwole et al.
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Cough causes concern for parents and is a major cause of outpatient visits. It can impact on quality of life, cause anxiety and affect sleep in parents and children. Several remedies, including honey, have been used to alleviate cough symptoms.
Takashi Koyanagi et al.
Xenobiotica; the fate of foreign compounds in biological systems, 44(10), 893-901 (2014-03-22)
1. The pharmacokinetics of acetaminophen (marker of gastric emptying), antipyrine (marker of hepatic metabolic activity and total body water), diazepam (lipophilic and highly distributed), diphenhydramine (hepatic blood flow-limited and alpha-1 acid glycoprotein bound) and ofloxacin (renally eliminated) were evaluated in
Makiko Kido-Nakahara et al.
The Journal of clinical investigation, 124(6), 2683-2695 (2014-05-09)
In humans, pruritus (itch) is a common but poorly understood symptom in numerous skin and systemic diseases. Endothelin 1 (ET-1) evokes histamine-independent pruritus in mammals through activation of its cognate G protein-coupled receptor endothelin A receptor (ETAR). Here, we have