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Merck

1440808

USP

Metoclopramide hydrochloride

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide monohydrochloride monohydrate, Metoclopramide monohydrochloride monohydrate

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Acerca de este artículo

Fórmula empírica (notación de Hill):
C14H22ClN3O2 · HCl · H2O
Número CAS:
Peso molecular:
354.27
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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Nombre del producto

Metoclopramide hydrochloride, United States Pharmacopeia (USP) Reference Standard

SMILES string

[Cl-].Clc1c(cc(c(c1)C(=O)NCCN(CC)CC)OC)N.O.[H+]

InChI

1S/C14H22ClN3O2.ClH.H2O/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H;1H2

InChI key

KJBLQGHJOCAOJP-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

metoclopramide

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Metoclopramide hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Metoclopramide Tablets
  • Metoclopramide Oral Solution
  • Metoclopramide Injection
  • Prazosin Hydrochloride

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Diana Egerton-Warburton et al.
Emergency medicine Australasia : EMA, 25(3), 207-212 (2013-06-14)
The study aims to determine if slow intravenous infusion of metoclopramide reduces the incidence of acute drug-induced akathisia (DIA) compared with intravenous bolus. A prospective, double-blind, double dummy trial of adult patients requiring intravenous metoclopramide in the ED. Participants were
Jian-qin Lv et al.
Trials, 14, 153-153 (2013-05-29)
The incidence of postoperative nausea and vomiting (PONV) is 50 to 79% after neurosurgery. Our study is designed to evaluate the efficacy of pericardium 6 (P6; also known as Neiguan) acupoint stimulation versus placebo, and versus routine antiemetic for the
Anastasios Koulaouzidis et al.
Current medical research and opinion, 29(9), 1171-1185 (2013-06-25)
The use of purging for bowel cleansing prior to small-bowel capsule endoscopy (SBCE) has now been established in clinical practice. Despite that, the number of incomplete SBCEs is still around 15-20%. To date, the use of prokinetics in SBCE -
Ray M Merrill et al.
BMC psychiatry, 13, 152-152 (2013-05-30)
To identify the incidence rate of spontaneous dyskinesia (SD) and tardive dyskinesia (TD) in a general population and to examine the association between dykinesia and potential risk factors (exposure to metoclopramide [MCP], antipsychotic drugs, and history of diabetes and psychoses).
Benjamin W Friedman et al.
Neurology, 82(11), 976-983 (2014-02-14)
We compared the efficacy of IV valproate with metoclopramide and with ketorolac in patients presenting to an emergency department (ED) with acute migraine. This was a double-blind comparative efficacy trial. Patients were randomized to 1,000 mg sodium valproate, 10 mg

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