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Merck

1530503

USP

L-Phenylalanine

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

(S)-2-Amino-3-phenylpropionic acid

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Fórmula lineal:
C6H5CH2CH(NH2)CO2H
Número CAS:
Peso molecular:
165.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1910408
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Nombre del producto

L-Phenylalanine, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1

InChI key

COLNVLDHVKWLRT-QMMMGPOBSA-N

SMILES string

N[C@@H](Cc1ccccc1)C(O)=O

grade

pharmaceutical primary standard

API family

phenylalanine

manufacturer/tradename

USP

mp

270-275 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

L-Phenylalanine USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare internal standard, standard, Sample, and system suitability solution during the assay and impurity analysis by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
  • Acetylcysteine Solution
  • Acetylcysteine
  • Phenylalanine  
  • Glutathione

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Kun Li et al.
Journal of the American Chemical Society, 136(32), 11402-11411 (2014-07-24)
Extracellular matrix proteins adsorbed onto mineral surfaces exist in a unique environment where the structure and dynamics of the protein can be altered profoundly. To further elucidate how the mineral surface impacts molecular properties, we perform a comparative study of
Matthew M Robinson et al.
The Journal of clinical endocrinology and metabolism, 99(12), E2574-E2583 (2014-09-16)
Insulin and essential amino acids (EAAs) regulate skeletal muscle protein synthesis, yet their independent effects on mitochondrial protein synthesis (MiPS) and oxidative function remain to be clearly defined. The purpose of this study was to determine the effects of high
Nicola Longo et al.
Lancet (London, England), 384(9937), 37-44 (2014-04-20)
Phenylketonuria is an inherited disease caused by impaired activity of phenylalanine hydroxylase, the enzyme that converts phenylalanine to tyrosine, leading to accumulation of phenylalanine and subsequent neurocognitive dysfunction. Phenylalanine ammonia lyase is a prokaryotic enzyme that converts phenylalanine to ammonia
F J van Spronsen et al.
Journal of inherited metabolic disease, 32(1), 46-51 (2009-02-05)
In phenylketonuria, mental retardation is prevented by a diet that severely restricts natural protein and is supplemented with a phenylalanine-free amino acid mixture. The result is an almost normal outcome, although some neuropsychological disturbances remain. The pathology underlying cognitive dysfunction
Minghua Tang et al.
The American journal of clinical nutrition, 99(4), 891-898 (2014-01-17)
Data on the protein requirements of elderly adults are limited, because it is impractical to conduct repeated nitrogen balance protocols in these vulnerable humans. This study was designed to determine the dietary protein requirement of elderly women by using the

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