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Merck

1705006

USP

L-Tirosina

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

3-(4-Hidroxifenil)-L-alanina, Ácido (S)-2-Amino-3-(4-hidroxifenil)propiónico

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Fórmula lineal:
4-(HO)C6H4CH2CH(NH2)CO2H
Número CAS:
Peso molecular:
181.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
392441
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grade

pharmaceutical primary standard

API family

tyrosine

form

fine crystals

manufacturer/tradename

USP

mp

>300 °C (dec.) (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

SMILES string

N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1

InChI key

OUYCCCASQSFEME-QMMMGPOBSA-N

General description

ʟ-Tyrosine is a non-essential amino acid involved in the biosynthesis of catecholamines, thyroid hormones, and melanin. The USP ʟ-Tyrosine standard guarantees the purity and quality of this amino acid, supporting its use in peptide synthesis, cell culture media, and therapeutic development.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

ʟ-Tyrosine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Tyrosine
  • Glycyl-l-tyrosine
  • Levodopa
  • N-Acetyltyrosine
  • Hyaluronidase Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Aminoácido precursor de la dopamina y otras catecolaminas
Sales restrictions may apply.
This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.


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flash_point_f

Not applicable

flash_point_c

Not applicable

Clase de almacenamiento

11 - Combustible Solids



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Andrzej Slominski et al.
Pigment cell & melanoma research, 25(1), 14-27 (2011-08-13)
There is evidence that L-tyrosine and L-dihydroxyphenylalanine (L-DOPA), besides serving as substrates and intermediates of melanogenesis, are also bioregulatory agents acting not only as inducers and positive regulators of melanogenesis but also as regulators of other cellular functions. These can
Maria B Feeney et al.
Antioxidants & redox signaling, 17(11), 1571-1579 (2012-03-20)
The understanding of physiological and pathological processes involving protein oxidation, particularly under conditions of aging and oxidative stress, can be aided by proteomic identification of proteins that accumulate oxidative post-translational modifications only if these detected modifications are connected to functional
Verena Rahm et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(4), 546-550 (2014-02-26)
Low-grade gliomas (LGGs) may harbor malignant foci, which are characterized by increased tumor cellularity and angiogenesis. We used diffusion-weighted MR imaging (apparent diffusion coefficient [ADC]) and PET with the amino acid O-(2-(18)F-fluorethyl)-L-tyrosine ((18)F-FET) to search for focal changes of diffusion