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Merck

1.37028

グリセロール

greener alternative

anhydrous (vegetable), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, ACS, USP

別名:

1,2,3-プロパントリオール, グリセリン

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この商品について

化学式:
HOCH2CH(OH)CH2OH
CAS番号:
56-81-5
分子量:
92.09
EC Index Number:
200-289-5
UNSPSC Code:
12352104
Beilstein/REAXYS Number:
635685
MDL number:
MFCD00004722

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製品名

グリセロール, anhydrous (vegetable), EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, ACS, USP

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

grade

ACS reagent

agency

BP
ChP
JP
Ph. Eur.
USP

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

product line

EMPROVE® EXPERT

assay

≤98.0-101.0% (calculated on anhydrous substance, alkalimetric)
≥99.5% (calculated on anhydrous substance, GC)

form

liquid

autoignition temp.

698 °F

expl. lim.

2.6-11.3 % (v/v)

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

technique(s)

electrophoresis: suitable

refractive index

n20/D 1.474 (lit.)

pH

5 (20 °C, 100 g/L in H2O)

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

transition temp

flash point 199 °C

density

1.25 g/mL (lit.)

application(s)

liquid formulation
ophthalmics
parenterals
pharma/biopharma processes
pharmaceutical

greener alternative category

Aligned,

storage temp.

2-25°C

Quality Level

500

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関連するカテゴリー

Application

Glycerol can be used in a wide variety of solid, semi-solid and liquid formulations, including ophthalmic, oral solid and oral liquid dosages, tablet coatings, creams and gels. It is applied for its humectant, emollient, solvent/cosolvent, viscosity increasing, and plasticizer properties.
Glycerol anhydrous (vegetable) Emprove® Expert is low in endotoxins and bioburden, making it the right choice for your high-risk applications.

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a bio-based glycerol and is aligned with the 5th principle of Green Chemistry "Safer Solvents and Auxiliaries" and 7th principle "Use of Renewable Feedstock". Click here for more details.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類

10 - Combustible liquids

wgk

WGK 1

flash_point_f

390.2 °F - Pensky-Martens closed cup

flash_point_c

199 °C - Pensky-Martens closed cup

試験成績書（COA）

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資料

Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

Use of Stabilizers and Surfactants to Prevent Protein Aggregation

This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.

関連コンテンツ

Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

グローバルトレードアイテム番号

カタログ番号GTIN
1.37028.901004027269158149
1.37028.100004027269158132
1.37028.250004027269065126
1.37028.902504027269065157

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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