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この商品について
実験式(ヒル表記法):
C7H10N2
CAS番号:
分子量:
122.17
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
EC Number:
214-353-5
Beilstein/REAXYS Number:
110354
MDL number:
製品名
4-(ジメチルアミノ)ピリジン, purum, ≥98.0% (NT)
InChI key
VHYFNPMBLIVWCW-UHFFFAOYSA-N
InChI
1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3
SMILES string
CN(C)c1ccncc1
grade
purum
assay
≥98.0% (NT)
form
crystals
pellets
mp
108-110 °C (lit.)
111-114 °C
solubility
methanol: 0.1 g/mL, clear, colorless to almost colorless
functional group
amine
Quality Level
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関連するカテゴリー
Application
アシル化反応用の高効率触媒
4-(Dimethylamino)pyridine can be used:
- As a capping agent in the preparation of water-soluble gold nanoparticles.
- As an initiator in the polymerization of epoxy monomers.
- As an auxiliary reagent in the electroless preparation of gold nanotubes applicable in catalysis.
- As a catalyst in the preparation of γ- and δ-lactones via iodolactonization of γ,δ-unsaturated carboxylic acids.
General description
4-(Dimethylamino)pyridine is generally employed as a catalyst in the acylation of amines, alcohols, enolates, and phenols. It can also be used in the esterification of carboxylic acids. It is known to exhibit good catalytic activity in non-polar solvents.
Other Notes
Hypernucleophilic acylation catalyst.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1
target_organs
Nervous system
保管分類
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
255.2 °F
flash_point_c
124 °C
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
A. Hassner
Tetrahedron, 34, 2069-2069 (1978)
E.F. Scriben
Chemical Society Reviews, 13, 129-129 (1983)
Hoefle, G., et al.
Angewandte Chemie (International Edition in English), 90, 602-602 (1978)
Giovanna Cutrone et al.
Carbohydrate polymers, 223, 115085-115085 (2019-08-21)
Nanoparticles made of metal-organic frameworks (nanoMOFs) are becoming of increasing interest as drug carriers. However, engineered coatings such as poly(ethylene glycol) (PEG) based ones are required to prevent nanoMOFs recognition and clearance by the innate immune system, a prerequisite for
Yi Zhang et al.
ACS applied materials & interfaces, 11(50), 46427-46436 (2019-11-26)
A kind of specific cyclodextrin polyrotaxanes (PRs) drug delivery system was developed for an effective drug delivery and enhancing antitumor effect. In this work, we prepared the PR by using α-CD derivatives and dicarboxyl-PEG (Mn = 4200) self-assembling and end-capping
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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