12804
HBTU
≥98.0% (T), for peptide synthesis
동의어(들):
N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate, O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C11H16F6N5OP
CAS 번호:
Molecular Weight:
379.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
423-020-5
MDL number:
Beilstein/REAXYS Number:
7328329
제품 이름
HBTU, ≥98.0% (T)
InChI key
UQYZFNUUOSSNKT-UHFFFAOYSA-N
InChI
1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
SMILES string
F[P-](F)(F)(F)(F)F.CN(C)C(\On1nnc2ccccc12)=[N+](/C)C
assay
≥98.0% (T)
form
solid
reaction suitability
reaction type: Coupling Reactions
mp
200 °C (dec.) (lit.)
solubility
acetonitrile: 0.1 g/mL, clear
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
Quality Level
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General description
HBTU is a peptide coupling agent used in Fmoc-based solid-phase peptide synthesis.
Application
HBTU is a peptide coupling agent for peptide synthesis. It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol.
Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1A
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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