226947
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate
98%
동의어(들):
CHAPS
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C32H58N2O7S · xH2O
CAS 번호:
Molecular Weight:
614.88 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161902
MDL number:
description
zwitterionic
Quality Level
assay
98%
mol wt
614.88 g/mol (anhydrous basis)
technique(s)
ion chromatography: suitable, protein quantification: suitable
mp
157 °C (dec.) (lit.)
functional group
amide, amine, hydroxyl, sulfonic acid
SMILES string
O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InChI
1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
InChI key
SJCUTFKCLFLIFE-JWTJKVBLSA-N
General description
CHAPS is a stabilizing agent that can be used to prevent aggregation, precipitation or proteolysis of proteins in solution.
Application
Zwitterionic detergent for membrane protein solubilization.
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
저장 등급
11 - Combustible Solids
A J Bitonti et al.
Biochemistry, 21(15), 3650-3653 (1982-07-20)
Bovine brain adenylate cyclase was solubilized with 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS), sodium cholate, sodium deoxycholate, or these detergents plus (NH4)2SO4. The specific activity of the extract obtained with 13 mM CHAPS alone was several times those of the other detergent extracts with
Zerbe O
BioNMR in Drug Research, 420-420 (2006)
J E Rudzki et al.
Biochemistry, 23(17), 3843-3848 (1984-08-14)
Picosecond transient absorption spectra of rhodopsin and isorhodopsin were measured at room temperature with a double-beam laser spectrophotometer after excitation at 355 nm. Photolysis studies were performed on rhodopsin solubilized in two different detergents (digitonin and 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate). The resulting rhodopsin/bathorhodopsin