379921
Hydroxylamine hydrochloride
99.995% trace metals basis
동의어(들):
Hydroxylammonium chloride
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
NH2OH · HCl
CAS 번호:
Molecular Weight:
69.49
UNSPSC Code:
12352301
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-798-2
Beilstein/REAXYS Number:
3539763
MDL number:
Assay:
99.995% trace metals basis
assay
99.995% trace metals basis
form
powder, crystals or chunks
pH
2.5-3.5 (20 °C, 50 g/L)
mp
155-157 °C (dec.) (lit.)
density
1.67 g/mL at 25 °C (lit.)
SMILES string
Cl.NO
InChI
1S/ClH.H3NO/c;1-2/h1H;2H,1H2
InChI key
WTDHULULXKLSOZ-UHFFFAOYSA-N
Application
Reactant for preparation of:
- Organosilane amines as potent inhibitors and structural probes of influenza A virus M2 proton channel
- Lamellarin D analogues as inibitors of topoisomerase I and potential antitumor agents
- Azapeptide tocolytic agents as inhibitors of prostaglandin F2α receptor for preventing preterm labor
- Thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
- Orally bioavailable quinoline-based antidiabetic dipeptidyl peptidase IV inhibitors targeting Lys554
- Pyrimidine nucleoside derivatives with nitric oxide donors as antiviral agents
- Benzyladenosine compounds targeting adenosine A2A receptor and adenosine transporter for neuroprotection
- Naphthol derivatives as inhibitors of the vanilloid receptor TRPV1 with improved potency in rat cystometry models of urinary incontinence
Biochem/physiol Actions
MAO inhibitor; inhibits platelet aggregation.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
target_organs
spleen
저장 등급
4.1A - Other explosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Carine B Bourguet et al.
Journal of medicinal chemistry, 54(17), 6085-6097 (2011-07-22)
The prostaglandin-F2α (PGF2α) receptor (FP) was targeted to develop tocolytic agents for inhibiting preterm labor. Azabicycloalkane and azapeptide mimics 2-10 were synthesized based on the (3S,6S,9S)-indolizidin-2-one amino acid analogue PDC113.824 (1), which was shown to modulate FP by a biased
Salvatore Cananzi et al.
Bioorganic & medicinal chemistry, 19(16), 4971-4984 (2011-07-26)
A novel 5-oxa-6a,8-diazaindeno[2,1-b]phenanthren-7-one scaffold was designed and synthesized as an active analogue of the cytotoxic marine alkaloid Lamellarin D. The design was based on molecular modeling of the site of interaction of Lamellarin D with DNA-topoisomerase I cleavable complex, whereas
Jun Wang et al.
Journal of the American Chemical Society, 133(35), 13844-13847 (2011-08-09)
We describe the use of organosilanes as inhibitors and structural probes of a membrane protein, the M2 proton channel from influenza A virus. Organosilane amine inhibitors were found to be generally as potent as their carbon analogues in targeting WT