479306
cis-Diamineplatinum(II) dichloride
≥99.9% trace metals basis
동의어(들):
cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
Pt(NH3)2Cl2
CAS 번호:
Molecular Weight:
300.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
EC Number:
239-733-8
MDL number:
Quality Level
assay
≥99.9% trace metals basis
reaction suitability
core: platinum, reagent type: catalyst
mp
270 °C (lit.)
antibiotic activity spectrum
neoplastics
mode of action
DNA synthesis | interferes
SMILES string
N.N.Cl[Pt]Cl
InChI
1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChI key
LXZZYRPGZAFOLE-UHFFFAOYSA-L
Application
Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer.
cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.
Biochem/physiol Actions
Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.
signalword
Danger
target_organs
Respiratory system
저장 등급
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3