730971
2-(Diisopropylamino)ethyl methacrylate
97%, contains ~100 ppm monomethyl ether hydroquinone as inhibitor
동의어(들):
DPA, DPAEMA
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C12H23NO2
CAS 번호:
Molecular Weight:
213.32
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
240-772-8
MDL number:
Quality Level
assay
97%
form
liquid
contains
~100 ppm monomethyl ether hydroquinone as inhibitor
refractive index
n20/D 1.145
density
0.900 g/mL at 25 °C
storage temp.
2-8°C
SMILES string
CC(C)N(CCOC(=O)C(C)=C)C(C)C
InChI
1S/C12H23NO2/c1-9(2)12(14)15-8-7-13(10(3)4)11(5)6/h10-11H,1,7-8H2,2-6H3
InChI key
SVYHMICYJHWXIN-UHFFFAOYSA-N
General description
2-(Diisopropylamino)ethyl methacrylate (DPA) is a methacrylate class of monomer used to prepare various DPA-derived polymers, which includes poly(2-(diisopropylamino)ethyl methacrylate) (PDPA). PDPA is a water-soluble polymer, which exhibits sensitivity to changes in pH and temperature. At pH levels below its pKa value of approximately 6.5, PDPA undergoes a transition from hydrophobic to hydrophilic behavior. This transition is attributed to the protonation of its amino groups. These unique properties of PDPA polymers consequently make them very useful in various applications such as drug delivery, gene delivery, sensors, surfaces, membranes, and chromatography.
Application
2-(Diisopropylamino)ethyl methacrylate can be used:
- As a monomer in the synthesis of multi-responsive hyperbranched copolymers by combining poly(oligo(ethylene glycol)methyl methacrylate) (P(OEGMA)) and 2-(diisopropylamino)ethyl methacrylate (PDIPAEMA) using RAFT polymerization. These polymers find application in drug delivery, gene delivery and tissue engineering.
- A monomers in the synthesis of block copolymer poly(ethyleneglycol)-b-poly(2-(diisopropylamino)ethyl methacrylate) (PEG-b-PDPAEMA). These pH-responsive micelles can be used for enhanced intracellular drug delivery. The DPA monomer contributes to the pH-responsive nature of the copolymers.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
저장 등급
10 - Combustible liquids
wgk
WGK 3
flash_point_f
210.0 °F
flash_point_c
98.9 °C